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Burkholderia mallei isolated in Brazil

ABSTRACT: First draft genome for a Burkholderia mallei isolate originating from a glanderous mule from Brazil

PROVIDER: PRJEB20536 | ENA |

REPOSITORIES: ENA

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Dataset's files

Source:

			Action	DRS
	FXLG01.dat.gz	Other
	FXLG01.fasta.gz	Fasta.gz
	FXLG01.master.dat	Other
	FXLG01.dat.gz	Other

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Project description:Burkholderia mallei and Burkholderia pseudomallei are both potential biological threats agents. Melioidosis caused by B. pseudomallei is endemic in Southeast Asia and Northern Australia, while glanders caused by B. mallei infections are rare. Here we studied the proteomes of different B. mallei and B. pseudomallei isolates to determine species specific characteristics. Analyzing the expressed proteomes of B. mallei and B. pseudomallei revealed differences between B. mallei and B. pseudomallei but also between isolates from the same species. Expression of multiple virulence factors and proteins of several PKS/NRPS clusters was demonstrated. Proteome analysis can be used not only to identify bacteria but also to characterize the expression of important factors that putatively contribute to pathogenesis of B. mallei and B. pseudomallei.

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