Project description:Our goal was to investigate the transcriptomes changes on rats liver, brain, thymus, and spleen after exposure to an indoor school air mixture (SAM+) of polychlorinated biphenyls (PCBs). Female Sprague-Dawley rats were exposed to SAM+ at a concentration of 45.5±5.9 µg/m^3 Σ209PCB or filtered air (sham group) 4 h/day, 6 days/week for 13 weeks using nose-only exposure systems. Twenty-four hours after the final exposure, rats were euthanized by carbon dioxide inhalation followed by cervical dislocation. Cardiac blood was collected and organs were excised and stored at -80 °C until analysis.
Project description:A total of 30 days of exposure to cigarette smoke (CS) or indoor air was given to 8- 23 week-old female C57BL/6 mice, then proteomics analyses were used to determine the 24 impact of CS on ovarian reserve.
Project description:This is one of the validation datasets which goes with the manuscript published in Exposome titled an actionable annotation scoring framework for gas chromatography high resolution mass spectrometry. The dataset describes indoor and outdoor air samples collected using passive samplers from homes near natural gas compressor stations.
