Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Mus musculus

ABSTRACT: Mapping of transcription factor binding sites in mouse embryonic stem cells

PROVIDER: PRJNA106455 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR001985.fastq.gz	Fastqsanger.gz
	SRR001986.fastq.gz	Fastqsanger.gz
	SRR001987.fastq.gz	Fastqsanger.gz
	SRR001988.fastq.gz	Fastqsanger.gz
	SRR001989.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 66

Similar Datasets

Mus musculus

Project description:Mapping of transcription factor binding sites in mouse nephron progenitor cells

| PRJNA354557 | ENA

Mus musculus

Project description:Genome-wide mapping of Eset-binding sites and H3K9me3 state in mouse embryonic stem cells

| PRJNA118587 | ENA

Mus musculus

Project description:Genome-wide Sall1 and Nanog binding sites in mouse embryonic stem cells

| PRJNA133989 | ENA

Mus musculus

Project description:Genome-Wide Sox17 Binding Sites in Mouse Extraembryonic Endoderm and Embryonic Stem Cells

| PRJNA120621 | ENA

Testis expression in Mus musculus domesticus x Mus musculus musculus hybrid zone mice

Project description:We collected whole genome testis expression data from hybrid zone mice. We integrated GWAS mapping of testis expression traits and low testis weight to gain insight into the genetic basis of hybrid male sterility.

2014-12-04 | GSE61417 | GEO

Mus musculus

Project description:Identification of transcription factor Srf binding sites and histone 3 actetylated regions in mouse cardiomyocytes

| PRJNA141687 | ENA

Mus musculus embryonic germ cell transcriptome

Project description:Identification of the mouse embryonic germ cell transcriptome

2015-08-13 | GSE70360 | GEO

Mus musculus

Project description:Selective influence of Sox2 on POU transcription factor binding in embryonic and neural stem cells

| PRJNA286988 | ENA

Testis expression in Mus musculus domesticus WSB/EiJ x Mus musculus musculus PWD/PhJ F2 hybrids

Project description:To characterize the genetic basis of hybrid male sterility in detail, we used a systems genetics approach, integrating mapping of gene expression traits with sterility phenotypes and QTL. We measured genome-wide testis expression in 305 male F2s from a cross between wild-derived inbred strains of M. musculus musculus and M. m. domesticus. We identified several thousand cis- and trans-acting QTL contributing to expression variation (eQTL). Many trans eQTL cluster into eleven ‘hotspots,’ seven of which co-localize with QTL for sterility phenotypes identified in the cross. The number and clustering of trans eQTL - but not cis eQTL - were substantially lower when mapping was restricted to a ‘fertile’ subset of mice, providing evidence that trans eQTL hotspots are related to sterility. Functional annotation of transcripts with eQTL provides insights into the biological processes disrupted by sterility loci and guides prioritization of candidate genes. Using a conditional mapping approach, we identified eQTL dependent on interactions between loci, revealing a complex system of epistasis. Our results illuminate established patterns, including the role of the X chromosome in hybrid sterility.

2014-05-01 | GSE54089 | GEO

Mus musculus Stra8-deficient fetal ovary transcriptome

Project description:Identification of the mouse embryonic germ cell Stra8-/- transcriptome

2015-08-13 | GSE70359 | GEO