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Aggregatibacter actinomycetemcomitans

ABSTRACT: Comparative genomic analysis of Aggregatibacter actinomycetemcomitans strains during short term persistent infections using a pan-genome microarray

PROVIDER: PRJNA183945 | ENA |

REPOSITORIES: ENA

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Comparative genomic analysis of Aggregatibacter actinomycetemcomitans strains during short term persistent infections using a pan-genome microarray

Project description:To analyze the gain and lost of genes in Aggregatibacter actinomycetemcomitans during short-term persistent infection in the same host

2013-12-31 | GSE42953 | GEO

Comparative genomic analysis of Aggregatibacter actinomycetemcomitans strains during short term persistent infections using a pan-genome microarray

Project description:To analyze the gain and lost of genes in Aggregatibacter actinomycetemcomitans during short-term persistent infection in the same host The microarray was used to compare gene contents of 4 different pairs of Aggregatibacter actinomycetemcomitans strains (SCC393 vs A160, SCC1398 vs SCC4092, SCC2302 vs AAS4a, and S23A vs I23C), where each pair was isolated from an individual over time. Two biological duplicates were carried out for each strain.

2013-12-31 | E-GEOD-42953 | biostudies-arrayexpress

Aggregatibacter actinomycetemcomitans

Project description:Transcriptome analysis of Aggregatibacter actinomycetemcomitans strains isolated from the same individual during short term persistent infections using a pan-genome microarray

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Comparative genomic analysis of Aggregatibacter actinomycetemcomitans of JP2 and non-JP2 genotypes using a pan-genome microarray

Project description:To assess the performance of our custom-designed pan-genome microarray and characterize the differences in gene content between JP2 and non-JP2 genotypes of A. actinomycetemcomitans. Comparative genomic hybridization reactions were carried out to assess the performance of our pan-genome microarray by using genomic DNA of 11 previously sequenced Aggregatibacter actinomycetemcomitans strains (I23C, SCC1398, ANH9381, HK1651, D7S-1, D11S-1, I63B, SCC393, D18P-1, SCC2302, and D17P-2). The microarray was subsequently used for comparative genomic hybridization of 6 strains of JP2 (S067, A26, G111-1, G121-2, D41S-1, and HK1651) and 6 strains non-JP2 (I23C, SCC1398, ANH9381, ATCC29524, 194, and G104-2) genotypes of Aggregatibacter actinomycetemcomitans. Two biological duplicates were carried out for each strain.

2012-09-28 | E-GEOD-39143 | biostudies-arrayexpress

Effect of Catecholamines on the Dental Pathogen Aggregatibacter actinomycetemcomitans

2015-05-12 | GSE68749 | GEO

Effect of Catecholamines on the Dental Pathogen Aggregatibacter actinomycetemcomitans

Project description:The two-component system qseBC is a putative prokaryotic adrenergic receptor. In Aggregatibacter actinomycetemcomitans (Aa), it was shown that the qseBC responds significantly to the presence of both catecholamines and ferrous iron. In addition, growth is significantly increased in the presence of both. Therefore, we performed a custom Aa microarray in order to determine the effects of catecholamines and catecholamines and iron (CAT-Fe) on Aa. Aggregatibacter actinomycetemcomitans was grown in triplicate in a chemically defined media (CDM) supplemented with either 100uM of ferrous chloride or 50uM of norepinephrine or both. At mid-log, RNA was harvested using the Qiagen Lipid Tissue Minikit.

2015-05-12 | E-GEOD-68749 | biostudies-arrayexpress

Aggregatibacter actinomycetemcomitans

Project description:Aggregatibacter actinomycetemcomitans overview

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Project description:Comparative genomic analysis of Aggregatibacter actinomycetemcomitans of JP2 and non-JP2 genotypes using a pan-genome microarray

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Effect of infection with Aggregatibacter actinomycetemcomitans or Porphyromonas gingivalis on primary murine bone marrow-derived dendritic cells

2013-01-11 | GSE41383 | GEO

Effect of infection with Aggregatibacter actinomycetemcomitans or Porphyromonas gingivalis on primary murine bone marrow-derived dendritic cells

Project description:To determine the biological mechanisms underlying a dampened immune response to Porphyromonas gingivalis, as compared to Aggregatibacter actinomycetemcomitans challenge, we infected primary BMDCs with either pathogen or left uninfected Total RNA from uninfected BMDCs compared to BMDCs infected with either Aggregatibacter actinomycetemcomitans or Porphyromonas gingivalis

2013-01-11 | E-GEOD-41383 | biostudies-arrayexpress

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