Project description:Linking genomic lesions with minimal residual disease improves prognostic stratification in children with T-cell acute lymphoblastic leukaemia

| PRJNA171760 | ENA

Expression data of plasma microRNA from the healthy children and children who diagnosed with acute lymphoblastic leukemia

Project description:According to the status of children acute lymphoblastic leukemia,we collected samples from the new dignosed, complete remmission and relapsed.

2018-01-31 | GSE109868 | GEO

Homo sapiens

Project description:Characterisation of the genomic landscape of CRLF2 deregulated acute lymphoblastic leukaemia

| PRJNA325466 | ENA

Transcriptomic profiling of 2 cell lines from Down-Syndrome children with Acute Lymphoblastic Leukaemia (DS-ALL)

Project description:Two cell lines derived from 2 Down Syndrome children who developed Acute Lymphoblastic Leukaemia were profiled at the transcriptomic level (bulk RNAseq) and compared against their Patient-Derived Xenograft (PDX) of origin.

2024-07-10 | GSE245056 | GEO

Genome-scale DNA methylation profiling of TEL/AML positive childhood acute lymphoblastic leukaemia

Project description:DNA methylation profiling of 48 samples to determine a DNA methylation signature specific to leukaemic bone marrow samples. Matching Leukaemia bone marrow and day 28 remission bone marrow or post induction follow up (follow up up to 2 years post induction) genomic DNA were extracted from archived microscope smear slides from 11 children diagnosed with TEL/AML positive Acute Lymphoblastic Leukaemia (ALL). Unmatched bone marrow samples from an additional 8 children were also analysed. Primary tissue control samples from CD34+ and CD19+ bone marrow from adult and childhood samples as well as model cell lines (cancer and non cancerous) were compared to primary diseased samples. Disease specific DNA methylation changes were identified from these results and then verified using SEQUENOM EpiTYPER. A total of 48 samples were analysed by Infinium DNA methylation analysis. As per manufacturer's protocols. Replicates were performed on one primary tumour sample and one cell line sample.

2012-12-31 | E-GEOD-29189 | biostudies-arrayexpress

Project description:Integrated Genomic Analysis of Relapsed Childhood Acute Lymphoblastic Leukemia reveals therapeutic strategies

| PRJNA139217 | ENA

Homo sapiens

Project description:Genomic characterization implicates iAMP21 as a primary genetic event in childhood B-cell precursor acute lymphoblastic leukaemia

| PRJNA135021 | ENA

Relapsed Acute Lymphoblastic Leukemia (ALL): Genomic Analysis in Pediatric Patients

Project description:Relapsed Acute Lymphoblastic Leukemia (ALL): Genomic Analysis in Pediatric Patients

| PRJNA311978 | ENA