Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Human gut metagenome

ABSTRACT: Human-associated Metagenome

PROVIDER: PRJNA206071 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR871559.fastq.gz	Fastqsanger.gz
	SRR871561.fastq.gz	Fastqsanger.gz
	SRR871564.fastq.gz	Fastqsanger.gz
	SRR871565.fastq.gz	Fastqsanger.gz
	SRR871566.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 91

Similar Datasets

human gut metagenome

Project description:Human-associated Metagenome

| PRJNA206440 | ENA

human gut metagenome

Project description:Human associated fecal metagenome

| PRJNA535526 | ENA

Relating human gut metagenome and metaproteome

Project description:Gut microbiome research is rapidly moving towards the functional characterization of the microbiota by means of shotgun meta-omics. Here, we selected a cohort of healthy subjects from an indigenous and monitored Sardinian population to analyze their gut microbiota using both shotgun metagenomics and shotgun metaproteomics. We found a considerable divergence between genetic potential and functional activity of the human healthy gut microbiota, in spite of a quite comparable taxonomic structure revealed by the two approaches. Investigation of inter-individual variability of taxonomic features revealed Bacteroides and Akkermansia as remarkably conserved and variable in abundance within the population, respectively. Firmicutes-driven butyrogenesis (mainly due to Faecalibacterium spp.) was shown to be the functional activity with the higher expression rate and the lower inter-individual variability in the study cohort, highlighting the key importance of the biosynthesis of this microbial by-product for the gut homeostasis. The taxon-specific contribution to functional activities and metabolic tasks was also examined, giving insights into the peculiar role of several gut microbiota members in carbohydrate metabolism (including polysaccharide degradation, glycan transport, glycolysis and short-chain fatty acid production). In conclusion, our results provide useful indications regarding the main functions actively exerted by the gut microbiota members of a healthy human cohort, and support metaproteomics as a valuable approach to investigate the functional role of the gut microbiota in health and disease.

2017-07-19 | PXD005780 | Pride

Reconstruction of the personal information from human genome reads in gut metagenome sequencing data

Project description:Human DNA present in fecal samples can result in a small number of human reads in gut shotgun metagenomic sequencing data. However, it is currently unclear how much personal information can be reconstructed from such reads and this has not been quantitatively evaluated. Such a quantitative evaluation is necessary to clarify the ethical concerns related to data sharing and to enable the efficient use of human genetic information in stool samples, such as for research and forensics. Here, we used genomic approaches to reconstruct personal information from fecal metagenomes of 343 Japanese individuals with associated human genotype data. Our approach can be used to quantify the personal information contained within gut metagenome data.

| EGAS00001007027 | EGA

human gut metagenome

Project description:Mucosa-Associated Bacteria Metagenome

| PRJNA240346 | ENA

Gut metagenome/FR 2002 (Salosensaari et al. Nature Comms 2021)

Project description:The main goal of the project is the study the associations between the gut metagenome and human health. The dataset contains data for n=7211 FINRISK 2002 participants who underwent fecal sampling. Demultiplexed shallow shotgun metagenomic sequences were quality filtered and adapter trimmed using Atropos (Didion et al., 2017), and human filtered using Bowtie2 (Langmead and Salzberg, 2012).

| EGAS00001005038 | EGA

Gut metagenome/FINRISK 2002 (Salosensaari et al. Nature Comms 2021)

| EGAS00001005020 | EGA

human bile metagenome, human gut metagenome

Project description:human bile metagenome, human gut metagenome Metagenome

| PRJNA483108 | ENA

human gut metagenome

Project description:Human Metagenome

| PRJNA205420 | ENA

human gut metagenome

Project description:human gut metagenome Metagenome

| PRJNA510269 | ENA