Project description:Purpose: To explore the influence of Ruminococcus torques treatment in mice intestinal epithelia. Method: Mice were pretreated with antibiotics for 3 days, then mice were fed with a high-fat diet and gavaged with PBS or R. torques (108 CFU/mouse) every 3 days for 2 weeks. mRNA profiles were generated by deep sequencing.Results: Several signaling pathways were changed after R. torques treatment, including response to hypoxia pathway. R. torques treatment significantly inhibits Epas1-mediated transcription effect.
Project description:Strain Ruminococcus torques TSDC19.2-1.1 (species Ruminococcus torques) was isolated from the fecal microbiota of a USA female at time point zero (bacterial isolates were sequenced from this donor on day 0 and 47). The species name was assigned by genome clustering.
Project description:Strain Ruminococcus torques TS7.1-1.2 (species Ruminococcus torques) was isolated from the fecal microbiota of a USA female at time point zero (bacterial isolates were sequenced from this donor on day 0, 364, 399, and 484). The species name was assigned by genome clustering.
Project description:Strain Ruminococcus torques TS7.1-1.3 (species Ruminococcus torques) was isolated from the fecal microbiota of a USA female at time point zero (bacterial isolates were sequenced from this donor on day 0, 364, 399, and 484). The species name was assigned by genome clustering.
