Project description:Identification and expression analysis of microRNAs in infected larvae of the insect model Galleria mellonella with uropathogenic (UPEC) and commensal E. coli strains that are known to cause symptomatic and asymptomatic bacteriuria (ABU) in humans, respectively.
Project description:MicroRNAs regulate differential innate immune response to uropathogenic and commensal-like Escherichia coli infection in the surrogate insect model Galleria mellonella
Project description:Insect cellular immunue plays an important role in recognition and eliminating the intruding entomopathogenic fungi. The genome-wide exprssion analysis involved in the cellular responses was analyzed by using high throughput sequencing (RNA-Seq). Our transcriptional profiles revealed that numerous differentially expressed genes (DEGs), of which involved in metabolism, immune system, cellular processing and so on, were significantly involved in the responses of G. mellonnella hemocytes.
Project description:The ascomycete fungus Beauveria bassiana is a pathogen of hundreds of insect species and is commercially produced as an environmentally friendly mycoinsecticide. Genome-wide insight into the infection of the fungi is critical for genetic improvement of fungal insecticides but has been poorly explored. We constructed three transcriptomes of Beauveria bassiana at 24, 48 and 72 hours post treatment of infection (BbI) and of control (Bbc).
Project description:Studies of bacterial community in G. mellonella larvae alone or infected with Heterorhabditis megidis nematodes; 16S and 18S rDNA loci
Project description:Transcriptional profiling of RNA in Galleria mellonella larvae during infection and at death by different entomopathogenic nematode species
