Project description:To determine how the mtDNA load at the beginning of tumorigenesis affects the DNA methylation patterns of TRFs during tumourigenesis. Different loads of mtDNA at the beginning of tumourigenesis have limited impact on the copy number variation contributing to tumorigenesis.
2018-12-31 | GSE98366 | GEO
Project description:How the levels of mtDNA copy number at the beginning of tumorigenesis affect DNA methylation profile during tumourigenesis.
Project description:Gene expression profiling of immortalized human mesenchymal stem cells with hTERT/E6/E7 transfected MSCs. hTERT may change gene expression in MSCs. Goal was to determine the gene expressions of immortalized MSCs.
Project description:Transcriptional profiling of human mesenchymal stem cells comparing normoxic MSCs cells with hypoxic MSCs cells. Hypoxia may inhibit senescence of MSCs during expansion. Goal was to determine the effects of hypoxia on global MSCs gene expression.
