Project description:Complete genome sequence and comparative analysis of Roseomonas mucosa from patients with atopic dermatitis or from healthy volunteers
Project description:Complete genome sequence and comparative analysis of Roseomonas mucosa from patients with atopic dermatitis or from healthy volunteers.
Project description:Complete genome sequence and comparative analysis of Roseomonas mucosa from patients with atopic dermatitis or from healthy volunteers.
Project description:Characteization host-microbiome interactions in patients with allergic (model: atopic dermatitis) and autoimmune (model: psoriasis) diseases by integration of microarray transcriptome data with 16S microbial profiling. 6mm punch biopsies were collected from the skin of atopic dermatitis and psoriasis patients alongside healthy volunteers, and subjected to analysis using Affymetrix Human Gene ST 2.1 arrays.
Project description:In this study we used genomic profiling to characterize differences in expression of genes related to epidermal growth/differentiation and inflammatory circuits in skin lesions of psoriasis and atopic dermatitis (AD), comparing expression values to normal skin. Skin biopsies were collected from 9 patients with chronic atopic dermatitis, 15 psoriasis patients, and 9 healthy volunteers. Keywords: Genetic-pathology