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Haloferax volcanii

ABSTRACT: Structural and functional adaptation of Haloferax volcanii TFEα/β

PROVIDER: PRJNA393790 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR5817006_1.fastq.gz	Fastqsanger.gz
	SRR5817006_2.fastq.gz	Fastqsanger.gz
	SRR5817007_1.fastq.gz	Fastqsanger.gz
	SRR5817007_2.fastq.gz	Fastqsanger.gz
	SRR5817008_1.fastq.gz	Fastqsanger.gz

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Project description:Purpose: The Haloferax volcanii ∆tfeB strain provided a unique opportunity to study a putative role of TFEβ in the regulation of gene expression. Results: The deletion of the tfeB gene in H. volcanii results in the aberrant expression of approximately one third of all genes, consistent with its function as a basal transcription initiation factor. Interestingly, tfeB deletion particularly affects foreign genes including a prophage region. Conclusions: Our results confirm the dual function of TFE as basal factor and regulator of transcription

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