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T47D Breast cancer cell line ChIP-seq data II

ABSTRACT: T47D Breast cancer cell line ChIP-seq data II

PROVIDER: PRJNA454709 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR7094751_1.fastq.gz	Fastqsanger.gz
	SRR7094751_2.fastq.gz	Fastqsanger.gz
	SRR7094752_1.fastq.gz	Fastqsanger.gz
	SRR7094752_2.fastq.gz	Fastqsanger.gz

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T47D Breast cancer cell line ChIP-seq data

Project description:T47D Breast cancer cell line ChIP-seq data

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T47D Breast cancer cell line ChIP-seq data II

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aCGH hybridization of breast cancer cell line T47D

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T47D Breast cancer cell line ChIP-seq data

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Project description:We report the comprehensive genome-wide binding peaks for key factors inovled in oxygen sensing pathways, such as HIF1α, HIF1β and EglN2. In addition, we also report the genome-wide binding peaks for NRF1 in breast cancer cells We conducted HA-EglN2, HIF1α, HIF1β (ARNT) or NRF1 ChIP-Seq in the T47D cell line that overexpresses HA-EglN2 in the presence of hypoxia (1%) and DMOG treatment. T47D parental cells treated with the same condition followed by HA ChIP-seq served as the control to filter non-specific binding.

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Baseline Expression of Inflammatory Cytokines and Receptors in the T47D Human Breast Cancer Cell Line

Project description:Immortalized human breast cancer cell line, T47D, was analyzed via RT-qPCR for transcript expression of selected inflammatory cytokines and cytokine receptors associated with promotion of tumor vasculature and breast cancer metastasis

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Phosphoproteomics of BYL719 (alpelisib)-Resistant T47D Human Breast Cancer Cell Line

Project description:The PI3Kalpha-specific inhibitor Alpelisib (BYL719) has been approved for the treatment of metastatic ER+/HER2- breast cancer patients in combination with Fulvestrant. After initial response, patients develop drug resistance and disease relapses. In order to identify signalling pathways contributing to the acquired resistance to BYL719 in breast cancer, we generated BYL719-resistant T47D cells and used them together with the parental cells to perform label-free quantitative phosphoproteomics.

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Next Generation Sequencing Facilitates Quantitative Analysis of human breast cancer cell T47D and T47D-TR Transcriptomes

Project description:To gain new insight into the resistance to hormonal therapy in breast cancer, we generated a tamoxifen-resistant human breast cancer cell line T47D-TR by exposing estrogen-sensitive cell line T47D to increasing concentrations of 4-hydroxy tamoxifen (4-OHT) and identified its resistance with different ways. What we interested is the underlying mechanisms of breast cancer tamoxifen resistance which was not reported yet.Here, we detect the RNA sequence of both the two cell lines hoping to find some evidence.

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SMAD2 binding regions in estrogen receptor-positive breast cancer cell line, T47D

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