Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Limosilactobacillus vaginalis strain:CBA-L88 (BV2)

ABSTRACT: Limosilactobacillus vaginalis strain:CBA-L88 (BV2) Genome sequencing and assembly

PROVIDER: PRJNA504605 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Limosilactobacillus vaginalis

Project description:Limosilactobacillus vaginalis Genome sequencing and assembly

| PRJNA566211 | ENA

Limosilactobacillus vaginalis

Project description:Lactobacillus vaginalis overview

| PRJNA37637 | ENA

Identification of Trichomonas vaginalis 5-nitroimidazole resistance targets

Project description:We aimed to delineate mechanisms of T. vaginalis resistance using transcriptome profiling of metronidazole (MTZ)-resistant and sensitive T. vaginalis clinical isolates.

2023-04-30 | GSE227448 | GEO

The transcriptional response of Trichomonas vaginalis to Trichomonas-derived extracellular vehicles

Project description:Trichomonas vaginalis, a common sexually transmitted parasite that colonizes the human urogenital tract, secretes extracellular vesicles (TvEVs) that are taken up by human cells and are speculated to be taken up by parasites as well. While the crosstalk between TvEVs and human cells has led to insight into host:parasite interactions, the role of TvEVs in infection have largely been one-sided, with little known about the effect of TvEV uptake by T. vaginalis. Approximately 11% of infections are found to be co-infections of multiple T. vaginalis strains. Clinical isolates often differ in their adherence to and cytolysis of host cells, underscoring the importance of understanding the effects of TvEV uptake within the parasite population. To address this question our lab observed the effects of EV uptake by T. vaginalis on parasite gene expression. Using RNA-seq, we showed that TvEVs upregulate expression of predicted parasite membrane proteins and identified a novel adherence factor, heteropolysaccharide binding protein (HPB2).

2024-05-28 | GSE253522 | GEO

Exosomal-miRNA sequencing of optineurin gene knockdown BV2 cells and wild type BV2 cells

Project description:To compare the miRNA profiles in exosomes derived from optineurin gene knockdown (Optn-KD)BV2s cells and wild type (WT) BV2 cells, BV2 cells were divided into two groups, Optn-KD group or WT group. We treated the Optn-KD group with Optn siRNA for 24 hours. Then, MiRNA profiles for each group were examined by Illumina HiSeq4000. We found differentiated miRNA profiles in the two groups. Compared with WT BV2 cell-derived exosomes, 4 miRNAs (miR-125b-5p, miR-351-5p, miR-505-5p, miR-novel-chr8_37700) were up-regulated and 2 miRNAs (miR-574-5p, miR-99b-5p) were down-regulated in Optn-KD BV2 cell-derived exosomes. This study provides a framework for characterizing the exosomal-miRNAs in Optn-KD BV2 cells.

2021-03-19 | GSE169175 | GEO

Limosilactobacillus reuteri strain:ZLR003

Project description:Limosilactobacillus reuteri strain:ZLR003 Assembly

| PRJNA290298 | ENA

Transcription profiling of Trichomonas vaginalis cultured in the low-iron and high-iron conditions

Project description:Transcriptional changes of Trichomonas vaginalis cultured in the low-iron and high-iron conditions.

2010-07-24 | E-MTAB-126 | biostudies-arrayexpress

Gardnerella vaginalis activates host responses necessary for Escherichia coli recurrent UTI from bladder reservoirs

Project description:Recurrent urinary tract infections (rUTI) are a costly clinical problem affecting millions of women worldwide each year. The majority of rUTI cases are caused by uropathogenic Escherichia coli (UPEC). Data from humans and mouse models indicate that some instances of rUTI are caused by UPEC emerging from latent reservoirs in the bladder. Some studies have reported that women with vaginal dysbiosis, typically characterized by high levels of Gardnerella vaginalis and other anaerobes, are at increased risk of UTI. Multiple studies have detected G. vaginalis in urine collected by transurethral catheterization (to limit vaginal contamination), suggesting that some women experience routine urinary tract exposures. We recently reported that inoculation of G. vaginalis into the bladder triggers rUTI from UPEC bladder reservoirs in a mouse model. Here we performed whole bladder RNAseq to identify host pathways involved in G. vaginalis-induced rUTI. We identified multiple host pathways differentially expressed following G. vaginalis exposure. At the gene and transcript level, we identified upregulation of the orphan nuclear receptor Nur77 (aka Nr4a1) and Nur77-regulated genes. Pilot data from Nur77 knockout mice suggests that Nur77 is necessary for G. vaganalis exposure to trigger rUTI.

2021-11-01 | GSE186800 | GEO

Streptococcus vaginalis strain:P1L01

Project description:Streptococcus vaginalis strain:P1L01 Genome sequencing and assembly

| PRJNA700462 | ENA

Gardnerella vaginalis strain:3549624

Project description:Gardnerella vaginalis strain:3549624 Genome sequencing and assembly

| PRJNA288563 | ENA