Project description:To identify changes in splicing patterns following TARBP2 knockdiwn, RNA-sequencing was performed on breast cancer cells transfected with siRNAs targeting TARBP2.
Project description:To identify changes in splicing patterns following TARBP2 knockdown, RNA-sequencing was performed on breast cancer cells transduced with shRNAs targeting TARBP2.
Project description:To identify changes in splicing patterns following TARBP2 knockdown, RNA-sequencing was performed on nuclear RNA extracted from cells expressing shRNAs targeting TARBP2 or a non-targeting shRNA (shControl).
Project description:To identify changes in methylation patterns following TARBP2 knockdown, m6A-IP followed by RNA-seq was performed on breast cancer cells expressing shRNAs against TARBP2 (and non-targeting shControl cells).
Project description:siRNA-mediated knock-down followed by transcriptomic profiling revealed that silencing of TARBP2 resulted in a significant up-regulation of sRSE-carrying transcripts.