Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ChIRP_seq data for Rrp6 project analysis in malaria (Plasmodium falciparum)

ABSTRACT: ChIRP_seq data for Rrp6 project analysis in malaria (Plasmodium falciparum)

PROVIDER: PRJNA550432 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

RNA_seq data for Rrp6 project analysis in malaria (Plasmodium falciparum)

Project description:RNA_seq data for Rrp6 project analysis in malaria (Plasmodium falciparum)

| PRJNA550429 | ENA

RIP_seq data for Rrp6 project analysis in malaria (Plasmodium falciparum)

Project description:RIP_seq data for Rrp6 project analysis in malaria (Plasmodium falciparum)

| PRJNA550430 | ENA

ChIP_seq data for Rrp6 project analysis in malaria (Plasmodium falciparum)

Project description:ChIP_seq data for Rrp6 project analysis in malaria (Plasmodium falciparum)

| PRJNA550431 | ENA

HIC_seq data for Rrp6 project analysis in malaria (Plasmodium falciparum)

Project description:HIC_seq data for Rrp6 project analysis in malaria (Plasmodium falciparum)

| PRJNA550433 | ENA

Transcriptional signature of CD4hiCD38hi T cells from patients with Plasmodium falciparum or Plasmodium knowlesi malaria

Project description:We observed by flow cytometry a population of CD4 T cells expressing very high levels of the coreceptor CD4 and the ectoenzyme CD38 (termed CD4hiCD38hi) in the peripheral blood of patients from Sabah and Papua with Plasmodium falciparum or Plasmodium knowlesi malaria. CD4hiCD38 T cells express genes associated with type 1 regulatory T cells.

2022-05-13 | GSE148655 | GEO

Replication origin mapping in the malaria parasite P. falciparum

Project description:Replication origin mapping in the malaria parasite Plasmodium falciparum

2022-08-04 | GSE210010 | GEO

Discovery of telomere repeat-binding factor in the malaria parasite Plasmodium falciparum

Project description:ChIP-seq experiments were performed for the putative telomere repeat-binding factor (PfTRF) in the malaria parasite Plasmodium falciparum strain 3D7. The gene encoding this factor (PF3D7_1209300) was endogenously tagged with either a GFP- or a 3xHA-tag and these transgenic parasite lines were used in ChIP-sequencing experiments. Sequencing of the ChIP and input libraries showed enrichment of PfTRF at all telomere-repeat containing chromosome ends (reference genome Plasmodium falciparum 3D7 from PlasmoDB version 6.1) as well as in all upsB var promoters.In addition,PfTRF was enriched at seven additional, intra-chromosomal sites and called in the PfTRF-HA ChIP-seq only. Plasmodium falciparum 3D7 parasites were generated with -GFP or -3xHA C-terminal tagged TRF (PF3D7_1209300). Nuclei were isolated from formaldehyde cross-linked schizont-stage transgenic parasites and used to prepare chromatin. Chromatin immunoprecipitations were performed using mouse anti-GFP (Roche Diagnostics, #11814460001) or rat anti-HA 3F10 (Roche Diagnostics, #12158167001). Sequencing libraries were prepared according to a Plasmodium-optimized library preparation procedure including KAPA polymerase-mediated PCR amplification.

2016-07-15 | E-GEOD-76537 | biostudies-arrayexpress

Plasmodium falciparum

Project description:Plasmodium falciparum malaria studies

| PRJNA447987 | ENA

Replication origin mapping in the malaria parasite Plasmodium falciparum

Project description:The malaria parasite Plasmodium falciparum replicates via schizogony: a fundamentally unusual type of cell cycle involving asynchronous replication of multiple nuclei within the same cytoplasm. It also has one of the most A/T-biased genomes ever sequenced. Here, we present the first comprehensive study of the specification and activation of DNA replication origins during Plasmodium schizogony. Potential replication origins were found to be abundant, with ORC1-binding sites detected every ~800 bp throughout the genome. They had no motif enrichment, but were biased towards areas of higher G/C content. Origin activation was then measured at single-molecule resolution via DNAscent technology, and was much less dense than ORC1-binding sites, with origins activated preferentially in areas of low transcriptional activity. Consistently, replication forks moved slowest through the most highly transcribed genes, suggesting that conflicts between transcription and origin firing inhibit efficient replication, and that P. falciparum has evolved its S-phase to minimise such conflicts.

2023-01-30 | GSE208757 | GEO

Transcriptome profiling reveals functional variation in Plasmodium falciparum parasites from controlled human malaria infection studies

Project description:The objective of this study is to characterize the overall transcriptome of P. falciparum NF54 derived from a controlled-human malaria infection (CHMI) study. Healthy, immunologically naïve human volunteers were infected intradermally or intravenously with different dosages of Plasmodium falciparum sporozoites (Sanaria® PfSPZ Challenge). Parasites were isolated from these volunteers and subjected to a range of in vitro culture generation prior to RNA collection.

2019-08-21 | GSE136076 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data