Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Adineta vaga L1 PacBio

PROVIDER: PRJNA558051 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR9886612_subreads.fastq.gz	Fastqsanger.gz
	SRR9900840_subreads.fastq.gz	Fastqsanger.gz
	SRR9900841_subreads.fastq.gz	Fastqsanger.gz
	SRR9900832_subreads.fastq.gz	Fastqsanger.gz
	SRR9900842_subreads.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 15

Similar Datasets

Adineta vaga isolate:MBL

Project description:Adineta vaga

| PRJNA313073 | ENA

Adineta vaga

Project description:Adineta vaga overview

| PRJNA195949 | ENA

Adineta vaga

Project description:Adineta vaga Genome sequencing

| PRJNA195603 | ENA

Genome sequencing of Adineta vaga

Project description:Genome sequencing of Adineta vaga

| PRJEB1171 | ENA

Adineta vaga

Project description:Adineta vaga Transcriptome or Gene expression

| PRJNA195592 | ENA

Adineta vaga

Project description:Population genomics of the bdelloid rotifer Adineta vaga

| PRJNA498886 | ENA

Adineta vaga strain:AD008

Project description:Adineta vaga chromosome-level genome sequencing and assembly

| PRJNA680543 | ENA

Horizontal acquisition of a DNA ligase improves DNA damage tolerance in eukaryotes

Project description:Bdelloid rotifers are part of the restricted circle of multicellular animals that can withstand a wide range of genotoxic stresses at any stage of their life cycle. In this study, bdelloid rotifer Adineta vaga was used as a model to decipher the molecular basis of their extreme tolerance. Proteomic analysis showed that a specific DNA ligase, different from those usually involved in DNA repair in eukaryotes, is strongly over-represented upon ionizing radiation. A phylogenetic analysis revealed its orthology to prokaryotic DNA ligase E, and its horizontal acquisition by bdelloid rotifers and plausibly other eukaryotes. The fungus Mortierella verticillata, having a single copy of this DNA Ligase E homolog, also exhibits an increased radiation tolerance with an over-expression of this DNA ligase E following X-ray exposure. We also provide evidence that A. vaga ligase E is a major contributor of DNA breaks ligation activity, which is a common step of all important DNA repair pathways. Consistently, its heterologous expression in human cell lines significantly improved their radio-tolerance. Overall, this study highlights the potential of horizontal gene transfers in eukaryotes, and their contribution to the adaptation to extreme conditions.

2024-01-24 | PXD043051 | Pride

10x Genomics Chromium WGS of Tursiops Aduncus

Project description:This data and additional PacBio Sequel data were collected from the same individual for a de-novo genome assembly

2022-01-01 | E-MTAB-7310 | biostudies-arrayexpress

RNA-seq (Illumina and PacBio) of hESC

Project description:We used PacBio data to identify more reliable transcripts from hESC, based on which we can estimate gene/transcript abundance better from Illumina data. PacBio long reads and Illumina short reads were generated from the same hESC cell line H1. PacBio reads were error-corrected by Illumina reads to identify transcripts. rSeq is used to estimate gene/transcript abundance of the identified transcriptome.

2013-10-30 | E-GEOD-51861 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data