Project description:Comparative genomic analysis of T. cruzi CLB vs Trypanosoma rangeli (strains SC, Choachí, C23, H14, R1625 and PIT10) and Trypanosoma conorhini
Project description:Trypanosoma brucei requires extensive uridine insertion and deletion RNA editing of most of their mitochondrial transcripts to generate translatable open reading frames. The RNA editing substrate binding complex (RESC) serves as the scaffold that coordinates the protein-protein and protein-RNA interactions during editing. This project is to characterize the interactome of RESC6 and RESC8 protein by TurboID. Three replicates of each condition were performed.