Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Genome-wide transcriptome analysis of human papillomavirus type 16 infected primary keratinocytes

ABSTRACT: Genome-wide transcriptome analysis of human papillomavirus type 16 infected primary keratinocytes

PROVIDER: PRJNA574042 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Genome-wide transcriptome analysis of human papillomavirus type 16 infected primary keratinocytes [monolayer]

Project description:Genome-wide transcriptome analysis of human papillomavirus type 16 infected primary keratinocytes [monolayer]

| PRJNA565235 | ENA

Genome-wide transcriptome analysis of human papillomavirus type 16 infected primary keratinocytes [monolayer]

Project description:HPV alters the host transcriptional program to establish infection and complete its lifecycle. Infection of keratinocytes has been difficult until our development of extracellular matrix (ECM) to cell transfer system that allows efficient infection of primary keratinocytes. Using this model, the transcriptional program of HPV infected keratinocytes at different times post infection was analyzed by mRNA-seq.

2019-11-10 | GSE137361 | GEO

Genome-wide transcriptome analysis of organotypic rafts derived from human papillomavirus type 16 infected primary keratinocytes [3D raft]

2019-11-10 | GSE137964 | GEO

Genome-wide transcriptome analysis of organotypic rafts derived from human papillomavirus type 16 infected primary keratinocytes [3D raft]

Project description:Genome-wide transcriptome analysis of organotypic rafts derived from human papillomavirus type 16 infected primary keratinocytes [3D raft]

| PRJNA574045 | ENA

Human Papillomavirus 16 E5 modulates the expression of host microRNAs

Project description:The effect of human papillomavirus 16 E5 oncogene on cellular gene expression in human epithelial cells was studied.

2011-09-01 | GSE24908 | GEO

Human Papillomavirus 16 E5 modulates the expression of host microRNAs

Project description:The effect of human papillomavirus 16 E5 oncogene on cellular gene expression in human epithelial cells was studied. Alterations in cellular gene expression due to human papillomavirus type 16 E5 oncogene were studied in triplicate microarray screens. Epithelial cells where E5 expression was induced for 0, 2, 4, 24, 48, 72 and 96h were compared to control cells.

2011-08-31 | E-GEOD-24908 | biostudies-arrayexpress

High-risk human papillomavirus E7 affects host keratinocyte DNA methylation

Project description:To investigate the extent of host methylome dysregulation by the human papillomavirus (HPV) oncoprotein E7, we performed methylome array analysis on normal immortalized keratinocytes from skin (NIKS), NIKS cells maintaining the HPV16 or 18 episomes (NIKS-16, NIKS-18, respectively), and NIKS cells maintaining the HPV-16 episome deficient in E7 expression (NIKS-16ΔE7).

2017-06-11 | GSE83261 | GEO

High-risk human papillomavirus E7 affects host keratinocyte gene expression

Project description:To investigate the extent of gene expression dysregulation by the human papillomavirus (HPV) oncoprotein E7, we performed global gene expression analysis on normal immortalized keratinocytes from skin (NIKS), NIKS cells maintaining the HPV16 or 18 episomes (NIKS-16, NIKS-18, respectively), and NIKS cells maintaining the HPV-16 episome deficient in E7 expression (NIKS-16ΔE7).

2017-06-11 | GSE83259 | GEO

Long non-coding RNA FAM83H-AS1 is regulated by human papillomavirus 16 E6 independently of p53 in cervical cancer cells

Project description:Global long non-coding RNA (lncRNA) expression profile in primary human keratinocytes post-expression of high-risk HPV-16 E6 oncoprotein Purpose: The goal of this study is to utlize high-throughput RNA sequencing (RNA-seq) to identify differentially expressed host lncRNAs with the presence of the high-risk HPV-16 E6 oncoprotein in primary human foreskin keratinocytes. Methods: Primary human foreskin keratinocytes (HEKa) stably expressing HPV-16 E6 compared to GFP control were analyzed, in triplicates, by RNA-seq (Illumina). qRT-PCR validation was performed using SYBR Green assays. Results: 151 up- and 100 down-regulated host lncRNAs were altered greater than 1.5-fold change in HEKa expressing HPV-16 E6 compared to GFP control cells. Altered expression of 16 genes (8 up- and 8 down-regulated) were confirmed by qRT-PCR, demonstrating the high-degree of sensitivity of the RNA-seq method. Conclusions: Our study represents the first global screening of host lncRNAs altered specifically by HPV-16 E6 oncoprotein expression.

2018-10-31 | GSE115334 | GEO

Genome-wide transcriptome analysis of human papillomavirus type 16 infected primary keratinocytes

Project description:This SuperSeries is composed of the SubSeries listed below.

2019-11-10 | GSE137965 | GEO