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RNA sequencing analysis of HCT116 cells following 24 hours of metabolic recovery from methionine restriction +/- small molecule treatment.

ABSTRACT: RNA sequencing analysis of HCT116 cells following 24 hours of metabolic recovery from methionine restriction +/- small molecule treatment.

PROVIDER: PRJNA576436 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR10244706_1.fastq.gz	Fastqsanger.gz
	SRR10244706_2.fastq.gz	Fastqsanger.gz
	SRR10244707_1.fastq.gz	Fastqsanger.gz
	SRR10244707_2.fastq.gz	Fastqsanger.gz
	SRR10244708_1.fastq.gz	Fastqsanger.gz

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RNA sequencing analysis of HCT116 cells following 24 hours of metabolic recovery from methionine restriction +/- small molecule treatment.

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Project description:The goals of this study were to compare the distribution of H3K4me3 before and after methionine restriction to understand how nutrient availability and alterations in methionine metabolism affect the epigenetic state and regulate gene transcription. To do this we performed ChIP-seq with an H3K4me3 antibody and RNA-seq using PolyA+ mRNA.

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