Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Microarray analysis of miRNA in breast cancer cell lines

ABSTRACT: Microarray analysis of miRNA in breast cancer cell lines

PROVIDER: PRJNA610632 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Microarray analysis of miRNA in breast cancer cell lines

Project description:Microarray analysis of miRNA in breast cancer cell lines

| PRJNA610632 | ENA

Microarray analysis of miRNA in breast cancer cell lines

Project description:The project aimed to identify miRNA that varied with tumourigenicity in human breast cell lines. The second objective was to identify miRNA that had differential expression between cell lines that varied in accordance with the abundance of the tetraspanin CD9 in the cell lines and the degree to which endogenous factors within these cell lines interacted with the 3'UTR of CD9 as determined by dual luciferase assay. These miRNA were considered potential regulators of the abundance of CD9 in breast cancer.

2020-05-21 | GSE146477 | GEO

miRNA microarray data of drug-resistant breast cancer cell lines after chemotherapy

Project description:miRNA microarray data of drug-resistant breast cancer cell lines after chemotherapy

| PRJNA996976 | ENA

miRNA expression in breast cancer cell lines

Project description:miRNA expression in breast cancer cell lines

| PRJNA497259 | ENA

miRNA expression in breast cancer cell lines

Project description:We analyzed the miRNA expression in 6 breast cancer cell lines from young (HCC1500, HCC1937) and old (MCF-7, MDA-MB-231, HCC1806 and MDA-MB-468) patients with breast cancer using the GeneChip® miRNA 2.0 Array (Affymetrix, Santa Clara, CA, USA).

2020-04-16 | GSE121396 | GEO

miRNA sequencing on triple negative breast cancer cell lines

Project description:miRNA sequencing on triple negative breast cancer cell lines

| PRJNA423034 | ENA

miRNA microarray data of drug-resistant breast cancer cell lines after chemotherapy

Project description:The impact of three different chemodrugs (Adriamycin, Taxotere, Cytoxan) on the breast cancer cell lines (MDA-MB-231, MDA-MB-468, HCC1395) was analyzed compared to the parental cell by Affymetrix microarray

2024-01-25 | GSE237873 | GEO

miRNA sequencing on triple negative breast cancer cell lines

Project description:This study consists of miRNA seq data of 26 triple negative breast cancer cell lines

2018-02-07 | GSE108286 | GEO

Breast Cancer Cell Secretome Analysis to Decipher miRNA Tumor Biology and Discover Potential Biomarkers

Project description:MicroRNA (miRNA/miR) miR526b and miR655 overexpressed tumor cell-free secretions promote breast cancer phenotypes in the tumor microenvironment (TME). However, the mechanisms of miRNA regulating TME have never been investigated. With mass spectrometry analysis of MCF7-miRNA-overexpressed versus miRNA-low MCF7-Mock tumor cell secretomes, we identified 34 novel secretory proteins coded by eight genes YWHAB, TXNDC12, MYL6B, SFN, FN1, PSMB6, PRDX4, and PEA15 those are differentially regulated. We used bioinformatic tools and systems biology approaches to identify these markers’ role in breast cancer. Gene ontology analysis showed that the top functions are related to apoptosis, oxidative stress, membrane transport, and motility, supporting miRNA-induced phenotypes. These secretory markers expression is high in breast tumors, and a strong positive correlation exists between upregulated markers’ mRNA expressions with miRNA cluster expression in luminal A breast tumors. Gene expression of secretome markers is higher in tumor tissues compared to normal samples, and immunohistochemistry data supported gene expression data. Moreover, both up and downregulated marker expressions are associated with breast cancer patient survival. miRNA regulates these marker protein expressions by targeting transcription factors of these genes. Premature miRNA (pri-miR526b and pri-miR655) are established breast cancer blood biomarkers. Here we report novel secretory markers upregulated by miR526b and miR655 (YWHAB, MYL6B, PSMB6, and PEA15) are significantly upregulated in breast cancer patients’ plasma, and are potential breast cancer biomarkers.

2023-05-10 | PXD031771 | Pride

Microarray analysis of lung cancer cell lines

Project description:Microarray analysis of lung cancer cell lines

| PRJNA597768 | ENA