Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Microbial Ecology of Wasting Disease in Pisaster ochraceus

PROVIDER: PRJNA637333 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other
	JACSEG01.dat.gz	Other
	JACSEG01.fasta.gz	Fasta.gz
	JACSEG01.master.dat	Other
	SRR11931172_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 270

Similar Datasets

Pisaster ochraceus

Project description:Pisaster ochraceus overview

| PRJNA299703 | ENA

An Initial Comparative Genomic Autopsy of Wasting Disease in Sea Stars

Project description:Beginning in 2013, sea stars throughout the Eastern North Pacific were decimated by wasting disease, also known as ‘asteroid idiopathic wasting syndrome’ (AIWS) due to its elusive etiology. The geographic extent and taxonomic scale of AIWS meant events leading up to the outbreak were heterogeneous, multifaceted, and oftentimes unobserved; progression from morbidity to death was rapid, leaving few tell-tale symptoms. Here we take a forensic genomic approach to discover candidate genes that may help explain sea star wasting syndrome. We report the first genome and annotation for P. ochraceus, along with differential gene expression (DGE) analyses in four size classes, three tissue types, and in symptomatic and asymptomatic individuals. We integrate nucleotide polymorphisms associated with survivors of the wasting disease outbreak, DGE associated with temperature treatments in P. ochraceus, and DGE associated with wasting in another asteroid Pycnopodia helianthoides. In P. ochraceus, we find DGE across all tissues, among size classes, and between asymptomatic and symptomatic individuals; the strongest wasting-associated DGE signal is in pyloric caecum. We also find previously identified outlier loci co-occur with differentially expressed genes. In cross-species comparisons of symptomatic and asymptomatic individuals, consistent responses distinguish genes associated with invertebrate innate immunity and chemical defense, consistent with context-dependent stress responses, defensive apoptosis, and tissue degradation. Our analyses thus highlight genomic constituents that may link suspected environmental drivers (elevated temperature) with intrinsic differences among individuals (age/size, alleles associated with susceptibility) that elicit organismal responses (e.g. coelomocyte proliferation) and manifest as sea star wasting mass mortality.

2020-02-19 | GSE144422 | GEO

Project description:16s amplicon sequencing V3-V4 region from Pisaster ochraceus samples with and without Sea Star Wasting Disease

| PRJNA407315 | ENA

Project description:Pisaster ochraceus Raw sequence reads

| PRJNA445895 | ENA

Pisaster ochraceus

Project description:Pisaster ochraceus Transcriptome or Gene expression

| PRJNA299406 | ENA

Project description:Genotype-based comparative transcriptomics of Pisaster ochraceus

| PRJNA357374 | ENA

Project description:Systems Biology and Molecular Ecology of Chronic Wasting Disease

| PRJNA417092 | ENA

Pisaster ochraceus isolate:M0D055189C

Project description:Pisaster ochraceus isolate:M0D055189C Genome sequencing and assembly

| PRJNA532896 | ENA

Pisaster Microbiome

Project description:The sea star, Pisaster ochraceus, has unique and dominant bacteria.

| PRJEB35121 | ENA

Sea Star Hypoxia as a driving force of Asteroid Wasting, as revealed by associated 16S rRNA sequencing.

Project description:Microbiome of Pisaster ochraceus during organic matter enrichment and Asterias forbesi under suboxic conditions

| PRJEB39144 | ENA

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data