Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Expression data from gastric cancer organoids

ABSTRACT: Expression data from gastric cancer organoids

PROVIDER: PRJNA645258 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Expression data from gastric cancer organoids

Project description:To understand the molecular basis of the acquisition of 5-FU resistance in gastric cancer stem cells, we established 5-FU-resistant gastric cancer organoids. We used microarrays to detail the global program of gene expression underlying 5-FU resistance and maintenance of stem cell properties in gastric cancer.

2020-07-10 | GSE154127 | GEO

Expression data from gastric cancer

Project description:Expression data from gastric cancer

| PRJNA796833 | ENA

RNA sequencing of human gastric cancer drug treatment organoids

Project description:Using RNA sequencing, we profile transcriptome dervied from human gastric cancer organoids after drug treatment.

2023-03-02 | GSE220137 | GEO

Expression data from 45 paired of gastric cancer tissues and gastric normal tissues

Project description:In this dataset, we include the expression data obtained from gastric cancer tissues and gastric normal tissues to determine the differentially expressed genes in gastric cancer tissues.

2014-11-08 | GSE63089 | GEO

Expression data from 5 paired of gastric cancer tissues and gastric normal tissues

2014-04-16 | GSE56807 | GEO

Expression data from gastric cancer

Project description:Gastric cancer is a most prevalent cancer with high mortality and strong invasiveness. Presently, there are many kinds of diagnosis and treatment methods, but the diagnosis rate of early gastric cancer is still not high, with a low five-year survival rate. Although the gastric cancer mechanism has been extensively studied, but the entire regulatory networks of gastric cancer is still unclear. We used microarrays to detect gene expression in NOL6 normal and knockdown gastric cancer cells a, and to identify differentially expressed genes in this program.

2022-01-14 | GSE193606 | GEO

Expression data from gastric cancer cell line SGC-7901

Project description:Expression data from gastric cancer cell line SGC-7901

| PRJNA616133 | ENA

Expression array data from human gastric cancer cell lines

Project description:Expression array data from human gastric cancer cell lines

| PRJNA420075 | ENA

Human gastric organoids (34 days)

Project description:Human embryonic stem cells (WA01) were differentiated in a step-wise manner into three-dimensional human gastric organoids (hGOs). At day 34 of differentiation, the hGOs were collected and analyzed by RNA-sequencing.

2014-09-09 | E-MTAB-2885 | biostudies-arrayexpress

Patient-derived organoids for precise medicine in gastric cancer

Project description:Gastric cancer (GC) is a challenging malignant disease among gastrointestinal tumors. The clinical treatments for GC include surgery, neoadjuvant therapy and adjuvant chemotherapy. As patients’ response to chemotherapeutic drugs varies, an approach to predict the efficacy of chemotherapeutic treatment is urgently needed. Here, a biorepository of 17 human gastric tumor organoids (GTOs) and 9 normal organoids (GNOs) derived from GC patients was established, which contains the intestinal, diffuse and mixed-type of GC. GTOs retained morphologic, histopathological and genetic features of the tumors from which they were derived, and patient-derived organoid xenograft model indicated tumorigenicity of organoids. GTOs responses to clinically respective chemotherapy treatment positively correlated with the individual patient’s clinical response. Meanwhile, GNOs, which maintained original characteristics of corresponding tissues, could be separated from GTOs. The use of GNOs predicted the cytotoxic effect of chemotherapy on the organism. Our study implies that patient-derived organoids predict GC patient responses to chemotherapy and provide a solution for personalized treatment.

2024-03-10 | GSE235912 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data