Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Determination of transcriptional start sites in the presence of GABA for Corynebacterium glutamicum

ABSTRACT: Determination of transcriptional start sites in the presence of GABA for Corynebacterium glutamicum

PROVIDER: PRJNA658771 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR12496972.fastq.gz	Fastqsanger.gz

Items per page:

1 - 1 of 1

Similar Datasets

Determination of transcriptional start sites in the presence of GABA for Corynebacterium glutamicum

Project description:In this study, we analyzed the regulation of ƴ-aminobutyrate (GABA) utilization in Corynebacterium glutamicum by the PucR-type transcriptional regulator GabR and by alternative nitrogen and carbon sources.

2020-09-29 | GSE156688 | GEO

Comparison of C. glutamicum growing with GABA as carbon source in the presence or absence of (NH4)2SO4.

Project description:γ-Aminobutyric acid (GABA) is a non-proteinogenic amino acid and widespread in nature from microorganisms to plants and animals. DNA microarray analysis revealed that the transcription of gabTDP was strongly increased in C. glutamicum wild type grown with GABA and urea compared to the same strain cultivated with glucose and urea. Remarkably, the presence of ammonia partially inhibited growth on GABA, and the reasons for it were also investigated in this study.

2020-03-25 | GSE138827 | GEO

Comparison of Corynebacterium glutamicum with GABA or glucose as carbon source

2020-03-25 | GSE138828 | GEO

A new metabolic route for the production of gamma-aminobutyric acid in Corynebacterium glutamicum

Project description:Corynebacterium glutamicum shows a great potential for the production of gamma-aminobutyric acid (GABA) from glucose fermentation via putrescine. GABA, a non-protein amino acid widespread in nature, is a component of pharmaceuticals, foods and the biodegradable plastic polyamide 4. Here, the effect of GABA in the growth of C. glutamicum was evaluated. It was estimated that the presence 1.1 M of GABA in the medium reduces the maximum growth rate of C. glutamicum to half. It was also shown that the presence of GABA in the medium negatively affects the growth of C. glutamicum in ethanol as sole carbon source. Furthermore, a new route for the production of GABA in C. glutamicum was established. GABA production from glucose fermentation via putrescine was achieved by plasmid-based overexpression of putrescine transaminase (PatA) and gamma-aminobutyraldehyde dehydrogenase (PatD) in a putrescine production strain. The resultant strain can produce 5.3 ± 0.1 g L-1 of GABA. GABA production was improved by avoiding the formation of N-acetylputrescine and by reducing the amount of nitrogen in CGXII medium. Deletion of the genes responsible for GABA catabolism and GABA re-uptake led to an increase in the GABA production of 21% achieving a titer 8.0 ± 0.3 g L-1 and an increase in the volumetric productivity of 41% reaching a productivity of 0.31 g L-1 h-1, the highest volumetric productivity achieved so far for GABA production in C. glutamicum from glucose fermentation in flasks fermentations. The results obtained hitherto are very promising and competitive compared to the traditional pathway for the production of GABA.

2015-10-22 | GSE74258 | GEO

Transcriptome analysis of Corynebacterium glutamicum in response to furfural presence

Project description:To understrand the altered global gene expression levels in C. glutamicum wild type in presence of furfural, transcriptome profiling was performed.

2015-01-01 | GSE55516 | GEO

Comparison of C. glutamicum growing with GABA as carbon source in the presence or absence of (NH4)2SO4.

Project description:Comparison of C. glutamicum growing with GABA as carbon source in the presence or absence of (NH4)2SO4.

| PRJNA577459 | ENA

Determination of Transcriptional start sites in S. aureus USA300 (JE2) during exponential phase

Project description:Transcriptional start sites determination of USA300 (JE2) by using dRNA-Seq

2016-05-04 | GSE67424 | GEO

Comparison of Corynebacterium glutamicum with GABA or glucose as carbon source

Project description:Comparison of Corynebacterium glutamicum with GABA or glucose as carbon source

| PRJNA577460 | ENA

Transcriptome analysis of Corynebacterium glutamicum in response to furfural presence

Project description:To understrand the altered global gene expression levels in C. glutamicum wild type in presence of furfural, transcriptome profiling was performed. Transcriptome profiles of the wild type grown in CgXII medium without furfural and with furfural stresses (each 6.5 mM, 13 mM, and 20 mM) were compared by using the samples taken at the OD600 of 6 (for the control and experiments). Each experiment was performed with a duplicate.

2015-01-01 | E-GEOD-55516 | biostudies-arrayexpress

Transcriptional response of Corynebacterium glutamicum ATCC 13032 to 2.5 mM indole

Project description:Differential gene expression analysis of C. glutamicum ATCC 13032 in presence of 2.5 mM indole compared to control conditions without indole. C. glutamicum ATCC 13032 cells were cultivated in CGXII minimal medium with 40 g per litre glucose in presence of 2.5 mM indole and harvested during exponential phase (o.d.600 4).

2020-12-31 | GSE159887 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data