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Enterococcus faecalis strain:person suffered from root canal infection | isolate:person suffered from root canal infection

ABSTRACT: Enterococcus faecalis strain:person suffered from root canal infection | isolate:person suffered from root canal infection Genome sequencing

PROVIDER: PRJNA662083 | ENA |

REPOSITORIES: ENA

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Enterococcus faecalis strain:person suffered from root canal infection | isolate:person suffered from root canal infection

Project description:Enterococcus faecalis strain:person suffered from root canal infection | isolate:person suffered from root canal infection Genome sequencing

| PRJNA662083 | ENA

Root canal microbiota

Project description:Root canal microbiota Metagenome

| PRJNA992641 | ENA

Enterococcus faecalis strain:E.faecalis | isolate:person suffered from endodonotic disease

Project description:Enterococcus faecalis strain:E.faecalis | isolate:person suffered from endodonotic disease Genome sequencing

| PRJNA639122 | ENA

Enterococcus faecalis strain:sample isolated from infected human root canal teeth | isolate:sample isolated from infected human root canal teeth

Project description:Enterococcus faecalis strain:sample isolated from infected human root canal teeth | isolate:sample isolated from infected human root canal teeth Genome sequencing

| PRJNA555261 | ENA

Anal Canal Cancer : subclassification

Project description:Etiologically linked to HPV infection, malignancies of the anal canal have substantially increased in incidence over the last 20 years. Although most anal squamous cell carcinomas (SCC) respond well to chemoradiotherapy, for undetermined reasons, a subgroup of patients experience a poor outcome. Despite cumulative efforts for discovering independent predictors for overall survival, both nodal status and tumor size are still the only reliable factors predicting patient outcome. In the present study, we correlated both proteomic signatures and clinicopathological features of neoplastic lesions arising from two distinct portions of the anal canal: the lower part (squamous zone) and the more proximal anal transitional zone. Although microdissected cancer cells appeared indistinguishable by morphology (squamous phenotype), unsupervised clustering analysis of the whole proteome significantly highlighted the heterogeneity that exists within anal canal tumors. More importantly, two region-specific subtypes of SCC were revealed. The expression profile (sensitivity/specificity) of several selected biomarkers (keratin filaments) further confirmed the subclassification of anal (pre)cancers based on their cellular origin. Less commonly detected compared to their counterparts located in the squamous mucosa, SCC originating in the transitional zone displayed more frequently a poor or basaloid differentiation and were significantly correlated with reduced disease-free and overall survivals. Taken together, we present for the first time direct evidence that anal canal SCC comprises two distinct entities with different cells of origin, proteomic signatures and survival rates. This study forms the basis for a novel dualistic classification of anal carcinoma with implications for management, outcome expectations and possibly therapeutic approaches.

2016-12-20 | PXD004859 | Pride

Gene expression profile in external auditory canal squamous cell carcinoma

Project description:External auditory canal squamous cell carcinoma (EACC) is very rare, only accounting for two thousandth of the head and neck cancer. However, the development mechanism of EACC remains unknown. By using gene expression microarray analysis, we aimed to find differentially expressed genes involved in ESCC development. We identified a wide spectrum of molecular signatures in EACC, including mRNA and lncRNA. The present study systematically analyzed the expression of mRNA and lncRNA in squamous cell carcinoma of the external auditory canal and normal external auditory canal tissues. We detect the transcriptomic changes between squamous cell carcinoma of the external auditory canal and normal external auditory canal tissues to identify potential tumor biomarkers in squamous cell carcinoma of the external auditory canal.

2018-02-14 | GSE98912 | GEO

Amphibalanus amphitrite Longitudinal Canal Tissue

Project description:Proteomic analysis of Amphibalanus amphitrite longitudinal canal tissue in comparison to sub-mantle/reproductive tissue to ascertain functional similarity.

2018-11-14 | PXD010743 | Pride

Dog ear canal microbiome

Project description:Dog ear canal microbiome

| PRJNA649402 | ENA

The 100-Person Wellness Project (HPWP)

Project description:The 100-Person Wellness Project (HPWP)

| PRJNA384485 | ENA

Single-cell technology reveals the heterogeneity of adipose tissue in human spinal canal

Project description:In order to study the heterogeneity of adipose tissue in the spinal canal, we used single-cell sequencing to sequence the subcutaneous fat and adipose tissue in the spinal canal of patients with lumbar surgery at different ages.

2024-02-25 | GSE225820 | GEO

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