Project description:Abdominal fat is considered negatively associated with egg production. Therefore, it is necessary to clarity the regulatory mechanism for the abdominal fat deposition of Muscovy duck.

2021-02-04 | GSE144727 | GEO

Nanopore-based full-length transcriptome sequencing of Muscovy duck (Cairina moschata) ovary.

Project description:Unlike mammals, studies on mechanisms that regulate waterfowl ovulation have been rarely reported. To advance our understanding of the ovulation differences in Muscovy duck, we utilized the Oxford Nanopore Technologies (ONT) to generate transcriptome data from 3 groups of female duck ovaries with ovulation differences (i.e., preovulation [PO], consecutive ovulation [CO], and inconsecutive ovulation [IO]). In this study, the full-length transcriptome data qualitative analysis showed that a total of 24,504 nonredundant full-length transcripts were generated, 19,060 new transcripts were discovered and 14,848 novel transcripts were successfully annotated. For the quantitative analysis, differentially expressed genes (DEGs) between the 3 groups were identified and functional properties were characterized. CTNNB1, IGF1, FOXO3, HSPA2, PTEN and SMC4 may be potential hub genes that regulate ovulation. Adhesion-related pathway, mTOR pathway, TGF-β signaling pathway and FoxO signaling pathway have been considered as important pathways that affect follicular development and ovulation. These results provide a more complete data source of full-length transcriptome for the further study of gene expression and genetics in Muscovy duck. The hub genes and potential mechanisms that affect the ovulation of Muscovy duck have been screened out to provide a scientific basis for breeding work to improve the reproduction performance of Muscovy duck.

| S-EPMC8253917 | biostudies-literature

Cairina moschata

Project description:Cairina moschata

| PRJNA839069 | ENA

Cairina moschata

Project description:Cairina moschata overview

| PRJNA398095 | ENA