Project description:We aim to the investigate the role of tamoxifen in breast cancer progression. LCC2 and MCF-7 cells were used as the resistant and sensitive model.

2018-12-26 | GSE118774 | GEO

ESRP1 knockdown in breast cancer cells

Project description:ESRP1 was knocked down in endocrine resistant LCC2 and LCC9 cells

2019-01-19 | GSE125355 | GEO

Genome wide expression change in LCC2 and MCF-7 cells

Project description:Genome wide expression change in LCC2 and MCF-7 cells

| PRJNA486779 | ENA

lncRNA, mRNA, miRNA and circRNA expression data from MCF-7, LCC2 and LCC9 cells

Project description:This SuperSeries is composed of the SubSeries listed below.

2020-11-18 | GSE159981 | GEO

mRNA and lncRNA expression profiles in MCF-7 breast cancer cells stably overexpressing pcDNA3.1-PinX1 and Empty Vector

Project description:To elucidate the molecular mechanism and signaling pathways that PinX1 is involved in, a Human LncRNA Array V2.0 (Arraystar, USA)-based genome wide screen of the alterations in lncRNA and mRNA expression profiles was performed in MCF-7 cells stably overexpressing PinX1. MCF-7 breast cancer cells were transfected with the pcDNA3.1-PinX1 and pcDNA3.1 empty vector and the microarray analysis were performed after the clonal selection of cells with a high expression level.

2013-09-30 | E-GEOD-46756 | biostudies-arrayexpress

A study of differential circRNA and lncRNA expressions in COVID-19-infected peripheral blood

Project description:we found a total of 570 circRNA that have difference, among which 155 are up-regulated and 415 are down-regulated; and 898 lncRNA that have difference, in which 414 are up-regulated and 484 are down-regulated; and 476 mRNA that have difference, in which 98 are up-regulated and 378 are down-regulated. In this work, we sequenced circRNA, lncRNA and mRNA from recurrent COVID-19 patients and healthy people, and compared the differences.

2021-02-11 | GSE166552 | GEO

The expression profile of circRNA, lncRNA and mRNA in the testis of STZ-induced diabetic rats

Project description:The number of patients with diabetes is increasing worldwide. Diabetic testicular damage can cause spermiogenesis disorders and sexual dysfunction. We thus explored the role of circRNA, lncRNA and mRNA in diabetic testicular damage, and revealed that they could serve as effective prevention and treatment therapeutic targets. Streptozotocin (STZ) was used to generate a rat model of type 2 diabetes. Rat testicular tissues were used for circRNA, lncRNA and mRNA sequencing.

2021-03-17 | GSE169130 | GEO

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