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MiR-124 synergism with ELAVL3 enhances target gene expression to promote neuronal maturity [HITS-CLIP]

ABSTRACT: MiR-124 synergism with ELAVL3 enhances target gene expression to promote neuronal maturity [HITS-CLIP]

PROVIDER: PRJNA676025 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR13023865.fastq.gz	Fastqsanger.gz
	SRR13023866.fastq.gz	Fastqsanger.gz
	SRR13023867.fastq.gz	Fastqsanger.gz
	SRR13023868.fastq.gz	Fastqsanger.gz

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MiR-124 synergism with ELAVL3 enhances target gene expression to promote neuronal maturity [HITS-CLIP]

Project description:Neuron-enriched microRNAs (miRNAs), miR-9/9* and miR-124 (miR-9/9*-124), direct cell fate switching of human fibroblasts to neurons when ectopically expressed by repressing anti-neurogenic genes. How these miRNAs function after the onset of the transcriptome switch to a neuronal fate remains unclear. Here, we identified direct targets of miRNAs by Argonaute (AGO) HITS-CLIP as reprogramming cells activate the neuronal program and reveal the role of miR-124 that directly promotes the expression of its target genes associated with neuronal development and function.

2021-05-25 | GSE161237 | GEO

MiR-124 synergism with ELAVL3 enhances target gene expression to promote neuronal maturity

Project description:MiR-124 synergism with ELAVL3 enhances target gene expression to promote neuronal maturity

| PRJNA676021 | ENA

MiR-124 synergism with ELAVL3 enhances target gene expression to promote neuronal maturity [TD_RNAseq]

Project description:MiR-124 synergism with ELAVL3 enhances target gene expression to promote neuronal maturity [TD_RNAseq]

| PRJNA676027 | ENA

MiR-124 synergism with ELAVL3 enhances target gene expression to promote neuronal maturity [Rat_Neurons_RNAseq]

Project description:MiR-124 synergism with ELAVL3 enhances target gene expression to promote neuronal maturity [Rat_Neurons_RNAseq]

| PRJNA676026 | ENA

MiR-124 synergism with ELAVL3 enhances target gene expression to promote neuronal maturity [HNs_RNAseq]

Project description:MiR-124 synergism with ELAVL3 enhances target gene expression to promote neuronal maturity [HNs_RNAseq]