Project description:The complete chloroplast (cp) genome sequence of Sinosenecio oldhamianus, a common medicinal plant is widely distributed in South China. The plastome is 150,926?bp in length, with one large single-copy region of 94,588?bp, one small single-copy region of 18,130?bp, and two inverted repeat (IR) regions of 24,852?bp. It contains 134 genes, including 87 protein-coding genes, 8 ribosomal RNA, and 37 transfer RNA. The phylogenetic tree shows that this species is a sister to the genus Ligularia. The published plastome within Sinosenecio provides significant insight for elucidating the phylogenetic relationship of taxa within tribe Compositae.