Project description:Isolation of human orthopneumovirus (respiratory syncytial virus) using air-liquid interface culture of human bronchial/tracheal epithelial cells

| PRJDB13228 | ENA

Human orthopneumovirus

Project description:Genome Sequencing of Respiratory Syncytial Virus (RSV) over a 30 year period to understand genetic and antigenic evolution and association of genetic variation with disease severity in infants

| PRJNA244854 | ENA

E-Predict Training Data Set and Examples

Project description:This series includes a 32-array training dataset used to evaluate E-Predict normalization and similarity metric parameters as well as 13 microarrays used as examples in (Urisman, et. al 2005). Training data set includes 15 independent HeLa RNAhybridizations (microarrays 1-15), 10 independent nasal lavage samples positive for Respiratory Syncytial virus (microarrays 16-25), and 7 independent nasal lavage samples positive for Influenza A virus (microarrays 26-32). Examples iclude a serum sample positive for Hepatitis B virus (microarray 33), a nasal lavage sample positive for both Influenza A virus and Respiratory Syncytial virus (microarray 34), and culture samples of 11 distinct Human Rhinovirus serotypes (microarrays 35-45). Keywords = virus detection, E-Predict, species identification, metagenomics

2010-06-10 | E-GEOD-2228 | biostudies-arrayexpress

Gene expression signatures of symptomatic respiratory viral infection in adults

Project description:Diagnosis of acute respiratory viral infection is currently based on clinical symptoms and pathogen detection. Use of host peripheral blood gene expression data to classify individuals with viral respiratory infection represents a novel means of infection diagnosis. We used microarrays to capture peripheral blood gene expression at baseline and time of peak symptoms in healthy volunteers infected intranasally with influenza A H3N2, respiratory syncytial virus or rhinovirus. We determined groups of coexpressed genes that accurately classified symptomatic versus asymptomatic individuals. We experimentally inoculated healthy volunteers with intranasal influenza, respiratory syncytial virus or rhinovirus. Symptoms were documented and peripheral blood samples drawn into PAXgene tubes for RNA isolation.

2009-08-06 | E-GEOD-17156 | biostudies-arrayexpress

Respiratory syncytial virus

Project description:Respiratory syncytial virus Genome sequencing and assembly

| PRJNA438443 | ENA