Differences of miRMA expression signitures for blood samples of children with high blood lead level and low blood lead level
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ABSTRACT:
PROVIDER: PRJNA783266 | ENA |
REPOSITORIES: ENA
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Project description:To further explore the effect of blood lead on miRNA expression in blood, children (aged 2-5 years) from kindergartens of Shaanxi province were divided into two groups and blood samples were collected. miRNA array was used to testify miRNA expression landscape between low blood lead level (BLL) group (0~ 50.00 g/L) and high BLL group (>50.00 g/L).Our data showed that 27 miRNAs were highly differentially expressed. Expression of miR-34b from this signiture was quantified by qRT-PCR,linear regression analysis showed that the correlation coefficient between blood lead level and miR-34b is 0.247, p <0.001, indicating that miR-34b was correlated with BLL.
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Project description:Analysis of the DNA methylation level in peripheral blood leukocytes from healthy children using the Illumina HumanMethylation450 BeadChip Groupings by family membership requested but not provided by submitter
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Project description:Analysis of the DNA methylation level in peripheral blood leukocytes from healthy children using the Illumina HumanMethylation450 BeadChip Groupings by family membership requested but not provided by submitter DNA methylation association study in healthy children
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Project description:Analysis of the DNA methylation level in peripheral blood leukocytes from healthy children using the Illumina HumanMethylation450 BeadChip Groupings by family membership requested but not provided by submitter
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