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Adenosine Alleviates Necrotizing Enterocolitis by Enhancing the Immunosuppressive Function of MDSCs in Newborns

ABSTRACT: Adenosine Alleviates Necrotizing Enterocolitis by Enhancing the Immunosuppressive Function of MDSCs in Newborns

PROVIDER: PRJNA827581 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR18779926_1.fastq.gz	Fastqsanger.gz
	SRR18779926_2.fastq.gz	Fastqsanger.gz
	SRR18779927_1.fastq.gz	Fastqsanger.gz
	SRR18779927_2.fastq.gz	Fastqsanger.gz
	SRR18779928_1.fastq.gz	Fastqsanger.gz

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Adenosine Alleviates Necrotizing Enterocolitis by Enhancing the Immunosuppressive Function of MDSCs in Newborns [cell]

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Adenosine Alleviates Necrotizing Enterocolitis by Enhancing the Immunosuppressive Function of MDSCs in Newborns [tissue]

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Transcription profiling time series of the effects of hypoxia, breast and formula feeding on a Rattus norvegicus model of necrotizing enterocolitis

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Adenosine Alleviates Necrotizing Enterocolitis by Enhancing the Immunosuppressive Function of MDSCs in Newborns

Project description:This SuperSeries is composed of the SubSeries listed below.

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Project description:Necrotizing enterocolitis is an intestinal disease induces rapid destruction of the epithelial monolayer of the neonatal intestine. Clinically relevant models of this disease are lacking. Using our novel microfluidic model of necrotizing enterocolitis, we characterized the response of intestinal epithelial cell-derived organoids to intestinal bacteria isolated from a neonate with fatal NEC. We subsequently used RNA-sequencing to determine the gene expression profile of these cells after 24 or 72 hours of incubation.

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