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Effects of NSUN6 deficiency by systematic transcriptomes and m5C profiles in mice across tissue [RNA-Seq]

ABSTRACT: Effects of NSUN6 deficiency by systematic transcriptomes and m5C profiles in mice across tissue [RNA-Seq]

PROVIDER: PRJNA827759 | ENA |

REPOSITORIES: ENA

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Effects of NSUN6 deficiency by systematic transcriptomes and m5C profiles in mice across tissue [RNA-Seq]

Project description:we constructed Nsun6-KO mouse, and observed that the wight and appearance of KO mice didn’t show abnormality. Through Bisulfite sequencing (BS-seq) in wild-type (WT) as well as KO mice and mRNA-seq, we identified high confident Nsun6-dependent m5C sites and performed the transcriptome analysis across five tissues.

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Effects of NSUN6 deficiency by systematic transcriptomes and m5C profiles in mice across tissue

Project description:Effects of NSUN6 deficiency by systematic transcriptomes and m5C profiles in mice across tissue

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Sequence- and structure-specific cytosine-5 methylation in mRNAs by NSUN6

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Effects of NSUN6 deficiency by systematic transcriptomes and m5C profiles in mice across tissue

Project description:This SuperSeries is composed of the SubSeries listed below.

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RNA m5C Methylation in breast cancer using MeRIP-Seq

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