Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Annotation of estrogen-regulated enhancer RNAs [ChIP-Seq]

ABSTRACT: Annotation of estrogen-regulated enhancer RNAs [ChIP-Seq]

PROVIDER: PRJNA832278 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR18925681.fastq.gz	Fastqsanger.gz
	SRR18925682.fastq.gz	Fastqsanger.gz
	SRR18925683.fastq.gz	Fastqsanger.gz
	SRR18925684.fastq.gz	Fastqsanger.gz
	SRR18925685.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 16

Similar Datasets

Annotation of estrogen-regulated enhancer RNAs

Project description:Annotation of estrogen-regulated enhancer RNAs

| PRJNA732433 | ENA

Annotation of estrogen-regulated enhancer RNAs [RNA-Seq]

Project description:Annotation of estrogen-regulated enhancer RNAs [RNA-Seq]

| PRJNA832279 | ENA

Annotation of estrogen-regulated enhancer RNAs [PRO-cap]

Project description:Annotation of estrogen-regulated enhancer RNAs [PRO-cap]

| PRJNA732438 | ENA

Annotation of estrogen-regulated enhancer RNAs [RNA-seq]

Project description:Annotation of estrogen-regulated enhancer RNAs [RNA-seq]

| PRJNA732439 | ENA

Annotation of estrogen-regulated enhancer RNAs [RNA-seq]

Project description:To annotate estrogen-regulated eRNAs in MCF-7 breast cancer cells, we used RNA-sequencing of polyA-depleted and polyA-enriched RNA fractions to assemble the gene bodies of eRNAs.

2022-06-16 | GSE175468 | GEO

Annotation of estrogen-regulated enhancer RNAs [PRO-cap]

Project description:To annotate estrogen-regulated eRNAs in MCF-7 breast cancer cells, we used precision nuclear run-on and sequencing of capped RNA (PRO-cap) to determine the transcription start sites of eRNAs.

2022-06-16 | GSE175467 | GEO

Annotation of estrogen-regulated enhancer RNAs [ChIP-Seq]

Project description:To study the effects of BCAS2, an eRNA-interacting protein, depletion on estrogen receptor alpha binding upon estrogen treatment.

2022-06-16 | GSE201596 | GEO

Annotation of estrogen-regulated enhancer RNAs [RNA-Seq]

Project description:To study the effects of BCAS2, an eRNA-interacting protein, depletion on estrogen-responsive genes.

2022-06-16 | GSE201595 | GEO

Annotation of estrogen-regulated enhancer RNAs

Project description:This SuperSeries is composed of the SubSeries listed below.

2022-06-16 | GSE175469 | GEO

Epigenomics-Based Identification of Estrogen-regulated Long Noncoding RNAs in ER+ Breast Cancer [ChIP-Seq]

Project description:Breast cancer is one of the most prevalent cancers in women worldwide. Through the regulation of many coding and non-coding target genes, estrogen (E2 or 17b-estradiol) and its nuclear receptor ERα play important roles in breast cancer development and progression. Despite intensive studies on estrogen-regulated coding genes over the past decades, molecular mechanisms underlying estrogen-regulated non-coding RNAs in breast cancer remain to be elucidated. Here, we performed extensive epigenomic studies including GRO-seq and ATAC-seq, and identified genome-wide estrogen-regulated long non-coding RNAs (lncRNAs). Similar to the coding targets of ERα, the transcription of estrogen-regulated lncRNAs correlates with the activation status of ERα-bound enhancers, measured by eRNA production, chromatin accessibility, and the occupancy of the enhancer regulatory components including P300, MED1, and ARID1B. Our 3D chromatin architecture analyses suggest that lncRNAs and their neighboring E2-resonsive coding genes, exemplified by LINC00160 and RUNX1, might be regulated as a 3D structural unit resulted from enhancer-promoter interactions. Finally, we evaluated the expression levels of LINC00160 and RUNX1 in various types of breast cancer and found that their expression positively correlated with the survival rate in ER+ breast cancer patients, implying that the estrogen-regulated LINC00160 and its neighboring RUNX1 might represent potential biomarkers for ER+ breast cancers.

2020-09-30 | GSE144926 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data