ABSTRACT: Ceftazidime-Avibactam Resistance Development following Ceftazidime-Avibactam-based therapy in critically-ill patients with infections caused by KPC-producing Klebsiella pneumoniae
Project description:Emergence of Ceftazidime-Avibactam resistant KPC-producing K. pneumoniae (KPC-Kp) during ceftazidime-avibactam-based antimicrobial treatment.
Project description:Using in vitro directed evolution, we show that mismatch repair-deficient Pseudomonas aeruginosa can engage novel resistance mechanisms to ceftazidime-avibactam.
2021-08-30 | GSE180086 | GEO
Project description:Ceftazidime-avibactam in combination with imipenem as salvage therapy for ST11 KPC-33-producing Klebsiella pneumoniae
| PRJNA812371 | ENA
Project description:KPC Variant KPC-93 associated with resistance to Ceftazidime-Avibactam
Project description:Genomic investigation of a multiclonal outbreak caused by KPC-producing Klebsiella pneumoniae resistant to ceftazidime/avibactam and meropenem/vaborbactam in Italy