Ontology highlight
ABSTRACT:
ORGANISM(S): Mus Musculus
SUBMITTER: Sarah Parker
PROVIDER: PXD017884 | panorama | Thu Apr 09 00:00:00 BST 2020
REPOSITORIES: PanoramaPublic
Stotland Aleksandr B AB Spivia Weston W Orosco Amanda A Andres Allen M AM Gottlieb Roberta A RA Van Eyk Jennifer E JE Parker Sarah J SJ
Journal of molecular and cellular cardiology 20200329
Mitochondria are the major source of cellular energy (ATP), as well as critical mediators of widespread functions such as cellular redox balance, apoptosis, and metabolic flux. The organelles play an especially important role in the maintenance of cardiac homeostasis; their inability to generate ATP following impairment due to ischemic damage has been directly linked to organ failure. Methods to quantify mitochondrial content are limited to low throughput immunoassays, measurement of mitochondri ...[more]