Proteomics

Dataset Information

0

HsPlasma_LMF


ABSTRACT: Human low-molecular weight (

INSTRUMENT(S): LTQ Orbitrap

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Plasma Non-glyco

SUBMITTER: Greening DW, Simpson RJ 

PROVIDER: PAe004835 | PeptideAtlas | 2010-12-31

REPOSITORIES: PeptideAtlas

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Publications

A centrifugal ultrafiltration strategy for isolating the low-molecular weight (<or=25K) component of human plasma proteome.

Greening David W DW   Simpson Richard J RJ  

Journal of proteomics 20090925 3


The low-molecular weight fraction (LMF) of the human plasma proteome is an invaluable source of biological information, especially in the context of identifying plasma-based biomarkers of disease. In this study, a separation and enrichment strategy based on centrifugal ultrafiltration was developed for the LMF (i.e., <or=25K) of plasma routinely prepared from normal, healthy volunteers. Four commercially-available filter membranes of similar nominal molecular weight cut-off (NMWC), but differing  ...[more]

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