Mm_synaptosome_iTRAQ_HCD
Ontology highlight
ABSTRACT:
REANALYSIS of: PXD000552
INSTRUMENT(S): LTQ Orbitrap Velos
ORGANISM(S): Mus Musculus
SUBMITTER:
PROVIDER: PAe005210 | PeptideAtlas | 2014-12-31
REPOSITORIES: PeptideAtlas
Publications
Deep and precise quantification of the mouse synaptosomal proteome reveals substantial remodeling during postnatal maturation.
Moczulska Kaja Ewa KE Pichler Peter P Schutzbier Michael M Schleiffer Alexander A Rumpel Simon S Mechtler Karl K
Journal of proteome research 20140922 10
During postnatal murine maturation, behavioral patterns emerge and become shaped by experience-dependent adaptations. During the same period, the morphology of dendritic spines, the morphological correlates of excitatory synapses, is known to change, and there is evidence of concurrent alterations of the synaptosomal protein machinery. To obtain comprehensive and quantitative insights in the developmental regulation of the proteome of synapses, we prepared cortical synaptosomal fractions from a ...[more]
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