Mm_iPS_iTRAQ
Ontology highlight
ABSTRACT:
REANALYSIS of: PXD000413
INSTRUMENT(S): LTQ Orbitrap Velos
ORGANISM(S): Mus Musculus
SUBMITTER: Hussein SM, et al.
PROVIDER: PAe005212 | PeptideAtlas | 2014-12-31
REPOSITORIES: PeptideAtlas
Publications
Genome-wide characterization of the routes to pluripotency.
Hussein Samer M I SM Puri Mira C MC Tonge Peter D PD Benevento Marco M Corso Andrew J AJ Clancy Jennifer L JL Mosbergen Rowland R Li Mira M Lee Dong-Sung DS Cloonan Nicole N Wood David L A DL Munoz Javier J Middleton Robert R Korn Othmar O Patel Hardip R HR White Carl A CA Shin Jong-Yeon JY Gauthier Maely E ME Lê Cao Kim-Anh KA Kim Jong-Il JI Mar Jessica C JC Shakiba Nika N Ritchie William W Rasko John E J JE Grimmond Sean M SM Zandstra Peter W PW Wells Christine A CA Preiss Thomas T Seo Jeong-Sun JS Heck Albert J R AJ Rogers Ian M IM Nagy Andras A
Nature 20141201 7530
Somatic cell reprogramming to a pluripotent state continues to challenge many of our assumptions about cellular specification, and despite major efforts, we lack a complete molecular characterization of the reprograming process. To address this gap in knowledge, we generated extensive transcriptomic, epigenomic and proteomic data sets describing the reprogramming routes leading from mouse embryonic fibroblasts to induced pluripotency. Through integrative analysis, we reveal that cells transition ...[more]
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