Proteomics

Dataset Information

0

Hs_MitoticExit_Phos_Silac_HCD


ABSTRACT: Global phosphoproteomic mapping of early mitotic exit in human hela cells, HCD

REANALYSIS of: PXD001559

INSTRUMENT(S): LTQ Orbitrap Velos

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Others

SUBMITTER: Andrew Burgess 

PROVIDER: PAe005254 | PeptideAtlas | 2015-12-31

REPOSITORIES: PeptideAtlas

Dataset's files

Source:
Action DRS
PAe005254_10253_tandem.params Other
PAe005254_README Other
PAe005254_Search_Results_10253_201601010159.properties Other
PAe005254_Search_Results_10253_201601010159.tar.gz Other
PAe005254_mzXML_201601010157.properties Other
Items per page:
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Publications

Global Phosphoproteomic Mapping of Early Mitotic Exit in Human Cells Identifies Novel Substrate Dephosphorylation Motifs.

McCloy Rachael A RA   Parker Benjamin L BL   Rogers Samuel S   Chaudhuri Rima R   Gayevskiy Velimir V   Hoffman Nolan J NJ   Ali Naveid N   Watkins D Neil DN   Daly Roger J RJ   James David E DE   Lorca Thierry T   Castro Anna A   Burgess Andrew A  

Molecular & cellular proteomics : MCP 20150608 8


Entry into mitosis is driven by the coordinated phosphorylation of thousands of proteins. For the cell to complete mitosis and divide into two identical daughter cells it must regulate dephosphorylation of these proteins in a highly ordered, temporal manner. There is currently a lack of a complete understanding of the phosphorylation changes that occur during the initial stages of mitotic exit in human cells. Therefore, we performed a large unbiased, global analysis to map the very first dephosp  ...[more]

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