MitoCheck (www.mitocheck.org) - Systematic phosphorylation analysis of human mitotic protein complexes
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Fourier Transform Ion Cyclotron Resonance Mass Spectrometer, instrument model
SUBMITTER: 
Otto Hudecz
PROVIDER: PRD000214 | Pride | 2013-06-19
REPOSITORIES: Pride
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Publications
Systematic phosphorylation analysis of human mitotic protein complexes.
Hegemann Björn B Hutchins James R A JR Hudecz Otto O Novatchkova Maria M Rameseder Jonathan J Sykora Martina M MM Liu Sihan S Mazanek Michael M Lénárt Péter P Hériché Jean-Karim JK Poser Ina I Kraut Norbert N Hyman Anthony A AA Yaffe Michael B MB Mechtler Karl K Peters Jan-Michael JM
Science signaling 20111108 198
Progression through mitosis depends on a large number of protein complexes that regulate the major structural and physiological changes necessary for faithful chromosome segregation. Most, if not all, of the mitotic processes are regulated by a set of mitotic protein kinases that control protein activity by phosphorylation. Although many mitotic phosphorylation events have been identified in proteome-scale mass spectrometry studies, information on how these phosphorylation sites are distributed ...[more]
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