Proteomics,Multiomics

Dataset Information

0

Staphylococcus aureus ranalexin iTRAQ experiment (10 salt cuts)


ABSTRACT: Not available

INSTRUMENT(S): QSTAR XL, instrument model

ORGANISM(S): Staphylococcus Aureus (strain Mrsa252)

SUBMITTER: Catherine Botting  

PROVIDER: PRD000312 | Pride | 2011-09-02

REPOSITORIES: Pride

Dataset's files

Source:
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Publications

Global network analysis of drug tolerance, mode of action and virulence in methicillin-resistant S. aureus.

Overton Ian M IM   Graham Shirley S   Gould Katherine A KA   Hinds Jason J   Botting Catherine H CH   Shirran Sally S   Barton Geoffrey J GJ   Coote Peter J PJ  

BMC systems biology 20110512


<h4>Background</h4>Staphylococcus aureus is a major human pathogen and strains resistant to existing treatments continue to emerge. Development of novel treatments is therefore important. Antimicrobial peptides represent a source of potential novel antibiotics to combat resistant bacteria such as Methicillin-Resistant Staphylococcus aureus (MRSA). A promising antimicrobial peptide is ranalexin, which has potent activity against Gram-positive bacteria, and particularly S. aureus. Understanding mo  ...[more]

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