Ontology highlight
ABSTRACT:
INSTRUMENT(S): instrument model, LTQ Velos
ORGANISM(S): Homo Sapiens (human)
SUBMITTER: Christopher Murray
PROVIDER: PRD000411 | Pride | 2012-01-16
REPOSITORIES: Pride
Items per page: 5 1 - 5 of 6 |
Murray Christopher I CI Uhrigshardt Helge H O'Meally Robert N RN Cole Robert N RN Van Eyk Jennifer E JE
Molecular & cellular proteomics : MCP 20111129 2
Redox-switches are critical cysteine thiols that are modified in response to changes in the cell's environment conferring a functional effect. S-nitrosylation (SNO) is emerging as an important modulator of these regulatory switches; however, much remains unknown about the nature of these specific cysteine residues and how oxidative signals are interpreted. Because of their labile nature, SNO-modifications are routinely detected using the biotin switch assay. Here, a new isotope coded cysteine th ...[more]