Proteomics

Dataset Information

0

Factor Xa PICS with chymotryptic peptide library


ABSTRACT: Factor Xa PICS with chymotryptic peptide library

INSTRUMENT(S): instrument model, QSTAR Pulsar

ORGANISM(S): Homo Sapiens (human)

SUBMITTER: Oliver Schilling  

PROVIDER: PRD000421 | Pride | 2011-10-14

REPOSITORIES: Pride

Dataset's files

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Publications

Factor Xa subsite mapping by proteome-derived peptide libraries improved using WebPICS, a resource for proteomic identification of cleavage sites.

Schilling Oliver O   auf dem Keller Ulrich U   Overall Christopher M CM  

Biological chemistry 20111101 11


Proteomic identification of protease cleavage site specificity (PICS) is a recent proteomic approach for the easy mapping of protease subsite preferences that determines both the prime- and non-prime side specificity concurrently. Here we greatly facilitate user access by providing an automated and simple web-based data-analysis resource termed WebPics (http://clipserve.clip.ubc.ca/pics/). We demonstrate the utility of WebPics analysis of PICS data by determining the substrate specificity of fac  ...[more]

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