Dataset Information
Methylobacterium extorquens AM1 on acetate
Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap, instrument model
ORGANISM(S): Methylobacterium Extorquens Group
SUBMITTER: 
Nathanael Delmotte
PROVIDER: PRD000445 | Pride | 2012-02-28
REPOSITORIES: Pride
Dataset's files
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Publications
The ethylmalonyl-CoA pathway is used in place of the glyoxylate cycle by Methylobacterium extorquens AM1 during growth on acetate.
The Journal of biological chemistry 20111121 1
Acetyl-CoA assimilation was extensively studied in organisms harboring the glyoxylate cycle. In this study, we analyzed the metabolism of the facultative methylotroph Methylobacterium extorquens AM1, which lacks isocitrate lyase, the key enzyme in the glyoxylate cycle, during growth on acetate. MS/MS-based proteomic analysis revealed that the protein repertoire of M. extorquens AM1 grown on acetate is similar to that of cells grown on methanol and includes enzymes of the ethylmalonyl-CoA (EMC) p ...[more]
