Proteomics

Dataset Information

0

Quantitative proteomic analysis of mpkCCD cells in response to long-term vasopressin exposure


ABSTRACT: Not available

OTHER RELATED OMICS DATASETS IN: PRJNA122629

INSTRUMENT(S): instrument model

ORGANISM(S): Mus Musculus (mouse)

SUBMITTER: Attila Csordas  

PROVIDER: PRD000492 | Pride | 2012-07-26

REPOSITORIES: Pride

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Publications

Quantitative protein and mRNA profiling shows selective post-transcriptional control of protein expression by vasopressin in kidney cells.

Khositseth Sookkasem S   Pisitkun Trairak T   Slentz Dane H DH   Wang Guanghui G   Hoffert Jason D JD   Knepper Mark A MA   Yu Ming-Jiun MJ  

Molecular & cellular proteomics : MCP 20101012 1


Previous studies in yeast have supported the view that post-transcriptional regulation of protein abundances may be more important than previously believed. Here we ask the question: "In a physiological regulatory process (the response of mammalian kidney cells to the hormone vasopressin), what fraction of the expressed proteome undergoes a change in abundance and what fraction of the regulated proteins have corresponding changes in mRNA levels?" In humans and other mammals, vasopressin fulfills  ...[more]

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