Dataset Information

Proteome driven re-evaluation and functional annotation of Streptococcus pyogenes SF370 genome.

ABSTRACT: Shotgun proteomic analysis for re-evaluation of genome S. pyogenes SF370, by using RP-HPLC ion trap MS/MS with six-frame database.

INSTRUMENT(S): LTQ Orbitrap, instrument model

ORGANISM(S): Streptococcus Pyogenes M1 Gas

SUBMITTER: Akira OKAMOTO

PROVIDER: PRD000562 | Pride | 2011-11-18

REPOSITORIES: Pride

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			Action	DRS
	PRIDE_Exp_Complete_Ac_19230.pride.mgf.gz	Mgf
	PRIDE_Exp_Complete_Ac_19230.pride.mztab.gz	Mztab
	PRIDE_Exp_Complete_Ac_19230.xml.gz	Xml
	PRIDE_Exp_Complete_Ac_19231.pride.mgf.gz	Mgf
	PRIDE_Exp_Complete_Ac_19231.pride.mztab.gz	Mztab

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Publications

Proteome driven re-evaluation and functional annotation of the Streptococcus pyogenes SF370 genome.

Okamoto Akira A Yamada Keiko K

BMC microbiology 20111110

<h4>Background</h4>The genome data of Streptococcus pyogenes SF370 has been widely used by many researchers and provides a vast array of interesting findings. Nevertheless, approximately 40% of genes remain classified as hypothetical proteins, and several coding sequences (CDSs) have been unrecognized. In this study, we attempted a shotgun proteomic analysis with a six-frame database that was independent of genome annotation.<h4>Results</h4>Nine proteins encoded by novel ORFs were found by shotg ...[more]

PMID: 22070424

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