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Intra-tumoral heterogenity of glioblsatoma multiforme

ABSTRACT: Quantitative proteomics analysis of different areas of glioblastoma with triplex Isotope-Coded Protein Label (ICPL)

INSTRUMENT(S): instrument model

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Brain

DISEASE(S): Brain Glioblastoma Multiforme

SUBMITTER: E Com

LAB HEAD: E Com

PROVIDER: PRD000580 | Pride | 2016-12-02

REPOSITORIES: Pride

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			Action	DRS
	PRIDE_Exp_Complete_Ac_19502.pride.mgf.gz	Mgf
	PRIDE_Exp_Complete_Ac_19502.xml.gz	Xml
	PRIDE_Exp_Complete_Ac_19503.pride.mgf.gz	Mgf
	PRIDE_Exp_Complete_Ac_19503.xml.gz	Xml
	PRIDE_Exp_Complete_Ac_19504.pride.mgf.gz	Mgf

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Quantitative proteomic Isotope-Coded Protein Label (ICPL) analysis reveals alteration of several functional processes in the glioblastoma.

Com Emmanuelle E Clavreul Anne A Lagarrigue Mélanie M Michalak Sophie S Menei Philippe P Pineau Charles C

Journal of proteomics 20120508 13

Glioblastoma (GB), the most frequent primary tumor of the central nervous system, remains one of the most lethal human cancers despite intensive researches. Current paradigm in the study of GB has been focused on inter-patient variability and on trying to isolate new classification elements or prognostic factors. Here, using ICPL, a technique for protein relative quantification by mass spectrometry, we investigated protein expression between the four regions of GB on clinically relevant biopsies ...[more]

PMID: 22575386

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