Dataset Information

INS-1 832/13 lipid droplet proteome

ABSTRACT: Not available

INSTRUMENT(S): instrument model

ORGANISM(S): Rattus Norvegicus (rat)

SUBMITTER: Svante Resjo

PROVIDER: PRD000592 | Pride | 2012-01-19

REPOSITORIES: Pride

ACCESS DATA

Dataset's files

Source:

			Action	DRS
	PRIDE_Exp_Complete_Ac_19827.pride.mgf.gz	Mgf
	PRIDE_Exp_Complete_Ac_19827.pride.mztab.gz	Mztab
	PRIDE_Exp_Complete_Ac_19827.xml.gz	Xml
	PRIDE_Exp_Complete_Ac_19828.pride.mgf.gz	Mgf
	PRIDE_Exp_Complete_Ac_19828.pride.mztab.gz	Mztab

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Publications

Characterization of the lipid droplet proteome of a clonal insulin-producing β-cell line (INS-1 832/13).

Larsson Sara S Resjö Svante S Gomez Maria F MF James Peter P Holm Cecilia C

Journal of proteome research 20120124 2

Lipids are known to play a crucial role both in the normal control of insulin release and in the deterioration of β-cell function, as observed in type 2 diabetes. Despite this established dual role of lipids, little is known about lipid storage and handling in β-cells. Here, we isolated lipid droplets from oleate-incubated INS-1 832/13 cells and characterized the lipid droplet proteome. In a total of four rounds of droplet isolation and proteomic analysis by HPLC-MS/MS, we identified 96 proteins ...[more]

PMID: 22268682

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