Proteomics

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Proteomic map of Leishmania - A proteogenomic approach to map the proteome of an unsequenced pathogen - Leishmania donovani


ABSTRACT: Proteomic map of Leishmania

INSTRUMENT(S): LTQ Orbitrap, instrument model

ORGANISM(S): Leishmania Infantum Jpcm5 Leishmania Donovani Leishmania Braziliensis Mhom/br/75/m2904 Leishmania Major Strain Friedlin

SUBMITTER: Akhilesh Pandey  

PROVIDER: PRD000608 | Pride | 2012-03-04

REPOSITORIES: Pride

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Visceral leishmaniasis or kala azar is the most severe form of leishmaniasis and is caused by the protozoan parasite Leishmania donovani. There is no published report on L. donovani genome sequence available till date, although the genome sequences of three related Leishmania species are already available. Thus, we took a proteogenomic approach to identify proteins from two different life stages of L. donovani. From our analysis of the promastigote (insect) and amastigote (human) stages of L. do  ...[more]

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