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The Arabidopsis Metacaspase 9 Degradome

ABSTRACT: The metacaspase 9 degradome in Arabidospis thaliana seedlings using N-terminal COFRADIC and further experimental validation of the identified substrates.

INSTRUMENT(S): LTQ Orbitrap, instrument model

ORGANISM(S): Arabidopsis Thaliana (mouse-ear Cress)

SUBMITTER: An Staes

PROVIDER: PRD000664 | Pride | 2013-08-13

REPOSITORIES: Pride

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Dataset's files

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			Action	DRS
	PRIDE_Exp_Complete_Ac_22147.pride.mgf.gz	Mgf
	PRIDE_Exp_Complete_Ac_22147.pride.mztab.gz	Mztab
	PRIDE_Exp_Complete_Ac_22147.xml.gz	Xml

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Publications

The Arabidopsis metacaspase9 degradome.

Tsiatsiani Liana L Timmerman Evy E De Bock Pieter-Jan PJ Vercammen Dominique D Stael Simon S van de Cotte Brigitte B Staes An A Goethals Marc M Beunens Tine T Van Damme Petra P Gevaert Kris K Van Breusegem Frank F

The Plant cell 20130820 8

Metacaspases are distant relatives of the metazoan caspases, found in plants, fungi, and protists. However, in contrast with caspases, information about the physiological substrates of metacaspases is still scarce. By means of N-terminal combined fractional diagonal chromatography, the physiological substrates of metacaspase9 (MC9; AT5G04200) were identified in young seedlings of Arabidopsis thaliana on the proteome-wide level, providing additional insight into MC9 cleavage specificity and revea ...[more]

PMID: 23964026

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